| Summary: | This study investigated the potential of pulsed electric field (PEF) extraction in enhancing the antimicrobial properties related to anti-acne and deodorant properties of <i>Hedychium coronarium</i> extract. The dried leaf and rhizome of <i>H. coronarium</i> were extracted using 95% <i>v</i>/<i>v</i> ethanol through both conventional solvent extraction and PEF extraction techniques (10, 14, and 20 kV/cm). The chemical composition of the extracts was analyzed. The antimicrobial activities, specifically in relation to acne treatment against <i>Cutibacterium acnes</i> and deodorant properties against <i>Staphylococcus aureus</i>, <i>Bacillus subtilis</i>, <i>Micrococcus luteus</i>, <i>Pseudomonas aeruginosa</i>, and <i>Escherichia coli</i>, were determined. The irritation profile of was evaluated using the hen’s egg chorioallantoic membrane test. The results showed that PEF extraction increased the extract yield, particularly at an electric field strength of 20 kV/cm. Furthermore, PEF extraction significantly enhanced the ellagic acid content, particularly in the leaf extract. Furthermore, the leaf extract demonstrated stronger inhibitory effects against microorganisms associated with body odor and acne compared to the rhizome extract. Notably, all extracts exhibited no signs of irritation, indicating their safety. Overall, the findings suggest that PEF extraction from <i>H. coronarium</i> enhances yield, bioactive compound content, and antimicrobial effects. This indicates the potential of the extract for acne treatment and deodorant use.
|
|---|