Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis
BackgroundIn recent years, hepatic arterial infusion chemotherapy (HAIC) has gained popularity in the treatment of hepatocellular carcinoma. Although several studies have been published, no bibliometric analysis have been conducted on this topic.ObjectivesTo understand the development status and fut...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1071860/full |
| _version_ | 1828071997875159040 |
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| author | Mei Li Mei Li Mei Li Kai Zhang Kai Zhang Kai Zhang Ji’an He Ji’an He Ji’an He Weihao Zhang Weihao Zhang Weihao Zhang Tianye Lv Tianye Lv Tianye Lv Li Wang Li Wang Li Wang Wenge Xing Wenge Xing Wenge Xing Haipeng Yu Haipeng Yu Haipeng Yu |
| author_facet | Mei Li Mei Li Mei Li Kai Zhang Kai Zhang Kai Zhang Ji’an He Ji’an He Ji’an He Weihao Zhang Weihao Zhang Weihao Zhang Tianye Lv Tianye Lv Tianye Lv Li Wang Li Wang Li Wang Wenge Xing Wenge Xing Wenge Xing Haipeng Yu Haipeng Yu Haipeng Yu |
| author_sort | Mei Li |
| collection | DOAJ |
| description | BackgroundIn recent years, hepatic arterial infusion chemotherapy (HAIC) has gained popularity in the treatment of hepatocellular carcinoma. Although several studies have been published, no bibliometric analysis have been conducted on this topic.ObjectivesTo understand the development status and future trends in the application of HAIC, we conducted bibliometric analysis to examine the cooperation and influence among countries, institutions, authors, and journals.MethodsAll relevant articles and reviews on the use of HAIC in HCC treatment were retrieved from the Web of Science database. A bibliometric analysis of countries, institutions, journals, authors, and keywords related to this field was performed using R and VOSviewer software. The main aspects analyzed were the research status and key fields of HAIC in HCC treatment.ResultsA total of 1026 articles published in 292 journals by 4937 authors from 959 institutions between 1974 and 2021 were retrieved. A rapid increase in articles published after 1990 was observed, which reached the peak in 2021. Japan had the most publications and citations. Yonsei University, Sun Yat-sen University, and Hiroshima University were the three leading institutions in research on this topic. Kwang-Hyub Han and Masatoshi Kudo have the greatest academic influence in this field. Most publications were made in the Hepato-Gastroenterology, whereas cancer had the most citations. The main aspects of HAIC treatment of HCC include HAIC and TACE, chemotherapy drug selection, HAIC and targeted therapy and immunotherapy, HAIC and surgery, and hepatotoxicity. Keywords such as FOLFOX, lenvatinib, hepatic arterial infusion chemotherapy are hot words in this field in recent years.ConclusionThe research on the use of HAIC in the treatment of HCC has been on the rise. Currently, HAIC combined with targeted therapy or immunotherapy has attracted significant attention. |
| first_indexed | 2024-04-11T01:02:24Z |
| format | Article |
| id | doaj.art-c69f421450094c72a198f1d90f11777f |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-11T01:02:24Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-c69f421450094c72a198f1d90f11777f2023-01-04T15:12:58ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-01-011210.3389/fonc.2022.10718601071860Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysisMei Li0Mei Li1Mei Li2Kai Zhang3Kai Zhang4Kai Zhang5Ji’an He6Ji’an He7Ji’an He8Weihao Zhang9Weihao Zhang10Weihao Zhang11Tianye Lv12Tianye Lv13Tianye Lv14Li Wang15Li Wang16Li Wang17Wenge Xing18Wenge Xing19Wenge Xing20Haipeng Yu21Haipeng Yu22Haipeng Yu23Department of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaDepartment of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaDepartment of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaDepartment of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaDepartment of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaDepartment of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaDepartment of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaDepartment of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, ChinaTianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaKey Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, ChinaBackgroundIn recent years, hepatic arterial infusion chemotherapy (HAIC) has gained popularity in the treatment of hepatocellular carcinoma. Although several studies have been published, no bibliometric analysis have been conducted on this topic.ObjectivesTo understand the development status and future trends in the application of HAIC, we conducted bibliometric analysis to examine the cooperation and influence among countries, institutions, authors, and journals.MethodsAll relevant articles and reviews on the use of HAIC in HCC treatment were retrieved from the Web of Science database. A bibliometric analysis of countries, institutions, journals, authors, and keywords related to this field was performed using R and VOSviewer software. The main aspects analyzed were the research status and key fields of HAIC in HCC treatment.ResultsA total of 1026 articles published in 292 journals by 4937 authors from 959 institutions between 1974 and 2021 were retrieved. A rapid increase in articles published after 1990 was observed, which reached the peak in 2021. Japan had the most publications and citations. Yonsei University, Sun Yat-sen University, and Hiroshima University were the three leading institutions in research on this topic. Kwang-Hyub Han and Masatoshi Kudo have the greatest academic influence in this field. Most publications were made in the Hepato-Gastroenterology, whereas cancer had the most citations. The main aspects of HAIC treatment of HCC include HAIC and TACE, chemotherapy drug selection, HAIC and targeted therapy and immunotherapy, HAIC and surgery, and hepatotoxicity. Keywords such as FOLFOX, lenvatinib, hepatic arterial infusion chemotherapy are hot words in this field in recent years.ConclusionThe research on the use of HAIC in the treatment of HCC has been on the rise. Currently, HAIC combined with targeted therapy or immunotherapy has attracted significant attention.https://www.frontiersin.org/articles/10.3389/fonc.2022.1071860/fullhepatocellular carcinomabibliometrichepatic arterial infusion chemotherapydata miningFOLFOX |
| spellingShingle | Mei Li Mei Li Mei Li Kai Zhang Kai Zhang Kai Zhang Ji’an He Ji’an He Ji’an He Weihao Zhang Weihao Zhang Weihao Zhang Tianye Lv Tianye Lv Tianye Lv Li Wang Li Wang Li Wang Wenge Xing Wenge Xing Wenge Xing Haipeng Yu Haipeng Yu Haipeng Yu Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis Frontiers in Oncology hepatocellular carcinoma bibliometric hepatic arterial infusion chemotherapy data mining FOLFOX |
| title | Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis |
| title_full | Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis |
| title_fullStr | Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis |
| title_full_unstemmed | Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis |
| title_short | Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis |
| title_sort | hepatic arterial infusion chemotherapy in hepatocellular carcinoma a bibliometric and knowledge map analysis |
| topic | hepatocellular carcinoma bibliometric hepatic arterial infusion chemotherapy data mining FOLFOX |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.1071860/full |
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