Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population.

Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population.

BACKGROUND: Recent genome-wide association studies (GWAS) have found a single nucleotide polymorphism (SNP, rs2274223 A>G) in PLCE1 to be associated with risk of gastric adenocarcinoma. In the present study, we validated this finding and also explored the risk associated with another unreported p...

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Main Authors: Mengyun Wang, Ruoxin Zhang, Jing He, Lixin Qiu, Jin Li, Yanong Wang, Menghong Sun, Yajun Yang, Jiucun Wang, Jingmin Yang, Ji Qian, Li Jin, Hongxia Ma, Qingyi Wei, Xiaoyan Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3295761?pdf=render

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