Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis

Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis

Objective: The nuclear receptor corepressor 1 (NCOR1) and the silencing mediator of retinoic acid and thyroid hormone (SMRT, also known as NCOR2) play critical and specific roles in nuclear receptor action. NCOR1, both in vitro and in vivo specifically regulates thyroid hormone (TH) action in the co...

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Bibliographic Details
Main Authors: Megan J. Ritter, Izuki Amano, Norihiro Imai, Lorraine Soares De Oliveira, Kristen R. Vella, Anthony N. Hollenberg
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Molecular Metabolism
Subjects:
Gene repression
Thyroid hormone
Nuclear corepressors
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001629

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