Acute Heart Failure Is a Malignant Process: But We Can Induce Remission
ABSTRACT Acute heart failure is a common and increasingly prevalent condition, affecting >10 million people annually. For those patients who survive to discharge, early readmissions and death rates are >30% everywhere on the planet, making it a malignant condition. Beyond these adverse outcome...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-11-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.123.031745 |
| _version_ | 1797400684636667904 |
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| author | Gad Cotter Beth A. Davison Carolyn S. P. Lam Marco Metra Piotr Ponikowski John R. Teerlink Alexandre Mebazaa |
| author_facet | Gad Cotter Beth A. Davison Carolyn S. P. Lam Marco Metra Piotr Ponikowski John R. Teerlink Alexandre Mebazaa |
| author_sort | Gad Cotter |
| collection | DOAJ |
| description | ABSTRACT Acute heart failure is a common and increasingly prevalent condition, affecting >10 million people annually. For those patients who survive to discharge, early readmissions and death rates are >30% everywhere on the planet, making it a malignant condition. Beyond these adverse outcomes, it represents one of the largest drivers of health care costs globally. Studies in the past 2 years have demonstrated that we can induce remissions in this malignant process if therapy is instituted rapidly, at the first acute heart failure episode, using full doses of all available effective medications. Multiple studies have demonstrated that this goal can be achieved safely and effectively. Now the urgent call is for all stakeholders, patients, physicians, payers, politicians, and the public at large to come together to address the gaps in implementation and enable health care providers to induce durable remissions in patients with acute heart failure. |
| first_indexed | 2024-03-09T01:59:02Z |
| format | Article |
| id | doaj.art-c6a2087c25fe44ab83966962b89fc22c |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-03-09T01:59:02Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-c6a2087c25fe44ab83966962b89fc22c2023-12-08T11:09:10ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802023-11-01122110.1161/JAHA.123.031745Acute Heart Failure Is a Malignant Process: But We Can Induce RemissionGad Cotter0Beth A. Davison1Carolyn S. P. Lam2Marco Metra3Piotr Ponikowski4John R. Teerlink5Alexandre Mebazaa6Heart Initiative Durham NCHeart Initiative Durham NCNational Heart Centre Singapore SingaporeCardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health University of Brescia Brescia ItalyInstitute of Heart Diseases, Wroclaw Medical University Wrocław PolandSection of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine University of California San Francisco San Francisco CAUniversité Paris Cité, INSERM UMR‐S 942 (MASCOT) Paris FranceABSTRACT Acute heart failure is a common and increasingly prevalent condition, affecting >10 million people annually. For those patients who survive to discharge, early readmissions and death rates are >30% everywhere on the planet, making it a malignant condition. Beyond these adverse outcomes, it represents one of the largest drivers of health care costs globally. Studies in the past 2 years have demonstrated that we can induce remissions in this malignant process if therapy is instituted rapidly, at the first acute heart failure episode, using full doses of all available effective medications. Multiple studies have demonstrated that this goal can be achieved safely and effectively. Now the urgent call is for all stakeholders, patients, physicians, payers, politicians, and the public at large to come together to address the gaps in implementation and enable health care providers to induce durable remissions in patients with acute heart failure.https://www.ahajournals.org/doi/10.1161/JAHA.123.031745acute heart failuremedicationsremission induction |
| spellingShingle | Gad Cotter Beth A. Davison Carolyn S. P. Lam Marco Metra Piotr Ponikowski John R. Teerlink Alexandre Mebazaa Acute Heart Failure Is a Malignant Process: But We Can Induce Remission Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease acute heart failure medications remission induction |
| title | Acute Heart Failure Is a Malignant Process: But We Can Induce Remission |
| title_full | Acute Heart Failure Is a Malignant Process: But We Can Induce Remission |
| title_fullStr | Acute Heart Failure Is a Malignant Process: But We Can Induce Remission |
| title_full_unstemmed | Acute Heart Failure Is a Malignant Process: But We Can Induce Remission |
| title_short | Acute Heart Failure Is a Malignant Process: But We Can Induce Remission |
| title_sort | acute heart failure is a malignant process but we can induce remission |
| topic | acute heart failure medications remission induction |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.123.031745 |
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