Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

A vaccine will likely be one of the key tools for ending the HIV-1/AIDS epidemic by preventing HIV-1 spread within uninfected populations and achieving a cure for people living with HIV-1. The currently prevailing view of the vaccine field is to introduce protective antibodies, nevertheless, a vacci...

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Bibliographic Details
Main Authors: Nathifa Moyo, Edmund G. Wee, Bette Korber, Kapil Bahl, Samantha Falcone, Sunny Himansu, Adrianne L. Wong, Antu K. Dey, Mark Feinberg, Tomáš Hanke
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Vaccines
Subjects:
HIV vaccine
HIVconsvX
HIVconsv
conserved regions
T cell vaccine
mRNA vaccines
Online Access:https://www.mdpi.com/2076-393X/8/3/360

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