Quickly finding orthologs as reciprocal best hits with BLAT, LAST, and UBLAST: how much do we miss?
Reciprocal Best Hits (RBH) are a common proxy for orthology in comparative genomics. Essentially, a RBH is found when the proteins encoded by two genes, each in a different genome, find each other as the best scoring match in the other genome. NCBI's BLAST is the software most usually used for...
| Những tác giả chính: | , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Public Library of Science (PLoS)
2014-01-01
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| Loạt: | PLoS ONE |
| Truy cập trực tuyến: | http://europepmc.org/articles/PMC4094424?pdf=render |