Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit
Background: Health care workers are in high risk of getting infected with hepatitis B virus. A large proportion of them do not receive a 3-dose series of hepatitis B vaccination and have anti hepatitis B surface antibody titer <10 mIU/ml. Materials and Methods: Health care workers of the hemo...
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| Format: | Article |
| Language: | English |
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Nobel Medical College Teaching Hospital
2020-12-01
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| Series: | Journal of Nobel Medical College |
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| Online Access: | https://www.nepjol.info/index.php/JoNMC/article/view/33354 |
| _version_ | 1831559598620803072 |
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| author | Shailendra Shrestha Pratap Roy |
| author_facet | Shailendra Shrestha Pratap Roy |
| author_sort | Shailendra Shrestha |
| collection | DOAJ |
| description | Background: Health care workers are in high risk of getting infected with hepatitis B virus. A large proportion of them do not receive a 3-dose series of hepatitis B vaccination and have anti hepatitis B surface antibody titer <10 mIU/ml.
Materials and Methods: Health care workers of the hemodialysis unit were included from March 2019 to March 2020 and were interviewed about hepatitis B vaccination status. Serum samples of the participants were analyzed for anti hepatitis B surface antibody titer. Participants with antibody titer of <10mIU/ml were given a 3-dose series of hepatitis B vaccination and antibody titer was again measured 1-2 months after the last dose.
Results: Among 30 participants, 19 (63.3%) had 3-dose series of hepatitis B vaccination, and all of them had anti hepatitis B antibody titer of >10 mIU/ml. Remaining 11 participants (36.7%), with either partial (6) or no hepatitis B vaccination (5), had antibody titer of <10mIU/ml. The mean ranks of antibody titer was significantly associated with the hepatitis B vaccination status (P<0.001). All 11 participants with antibody titer of <10 mIU/ml received a 3-dose series of hepatitis B vaccine and all of them achieved antibody titer >10 mIU/ml.
Conclusion: Our study shows that a large proportion of health care workers of hemodialysis unit were either partially or not vaccinated with hepatitis B vaccination and were having anti hepatitis B antibody titer of <10 mIU/ml. However, with complete 3-dose series of hepatitis B vaccination all of them achieved a protective antibody titer of ≥10 mIU/ml. |
| first_indexed | 2024-12-17T05:31:40Z |
| format | Article |
| id | doaj.art-c6a52167dc284a9d90b79318e0d86df7 |
| institution | Directory Open Access Journal |
| issn | 2091-2331 2091-234X |
| language | English |
| last_indexed | 2024-12-17T05:31:40Z |
| publishDate | 2020-12-01 |
| publisher | Nobel Medical College Teaching Hospital |
| record_format | Article |
| series | Journal of Nobel Medical College |
| spelling | doaj.art-c6a52167dc284a9d90b79318e0d86df72022-12-21T22:01:43ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2020-12-0192232710.3126/jonmc.v9i2.3335433354Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis UnitShailendra Shrestha0Pratap Roy1Department of Nephrology, Nobel Medical College Teaching Hospital, Biratnagar, NepalDepartment of Nephrology, Nobel Medical College Teaching Hospital, Biratnagar, NepalBackground: Health care workers are in high risk of getting infected with hepatitis B virus. A large proportion of them do not receive a 3-dose series of hepatitis B vaccination and have anti hepatitis B surface antibody titer <10 mIU/ml. Materials and Methods: Health care workers of the hemodialysis unit were included from March 2019 to March 2020 and were interviewed about hepatitis B vaccination status. Serum samples of the participants were analyzed for anti hepatitis B surface antibody titer. Participants with antibody titer of <10mIU/ml were given a 3-dose series of hepatitis B vaccination and antibody titer was again measured 1-2 months after the last dose. Results: Among 30 participants, 19 (63.3%) had 3-dose series of hepatitis B vaccination, and all of them had anti hepatitis B antibody titer of >10 mIU/ml. Remaining 11 participants (36.7%), with either partial (6) or no hepatitis B vaccination (5), had antibody titer of <10mIU/ml. The mean ranks of antibody titer was significantly associated with the hepatitis B vaccination status (P<0.001). All 11 participants with antibody titer of <10 mIU/ml received a 3-dose series of hepatitis B vaccine and all of them achieved antibody titer >10 mIU/ml. Conclusion: Our study shows that a large proportion of health care workers of hemodialysis unit were either partially or not vaccinated with hepatitis B vaccination and were having anti hepatitis B antibody titer of <10 mIU/ml. However, with complete 3-dose series of hepatitis B vaccination all of them achieved a protective antibody titer of ≥10 mIU/ml.https://www.nepjol.info/index.php/JoNMC/article/view/33354hepatitis brenal dialysisvaccination |
| spellingShingle | Shailendra Shrestha Pratap Roy Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit Journal of Nobel Medical College hepatitis b renal dialysis vaccination |
| title | Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit |
| title_full | Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit |
| title_fullStr | Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit |
| title_full_unstemmed | Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit |
| title_short | Hepatitis B Virus Vaccination Status and Anti Hepatitis B Surface Antibody Titer among the Health Care Workers of a Hemodialysis Unit |
| title_sort | hepatitis b virus vaccination status and anti hepatitis b surface antibody titer among the health care workers of a hemodialysis unit |
| topic | hepatitis b renal dialysis vaccination |
| url | https://www.nepjol.info/index.php/JoNMC/article/view/33354 |
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