Therapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad?
Accumulating evidence suggests that bone marrow-derived progenitor cells contribute to vascular healing and remodeling under physiologic and pathologic conditions. Although there is growing enthusiasm for therapeutic and diagnostic application of bone marrow-derived progenitors, there is a possibili...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM)
2007-03-01
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| Series: | International Journal of Gerontology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S187395980870019X |
| _version_ | 1818498519249453056 |
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| author | Kimie Tanaka Masataka Sata |
| author_facet | Kimie Tanaka Masataka Sata |
| author_sort | Kimie Tanaka |
| collection | DOAJ |
| description | Accumulating evidence suggests that bone marrow-derived progenitor cells contribute to vascular healing and remodeling under physiologic and pathologic conditions. Although there is growing enthusiasm for therapeutic and diagnostic application of bone marrow-derived progenitors, there is a possibility that transplanted precursors or bone marrow cells may participate in the pathogenesis of unexpected diseases such as cancer, retinopathy, and atherosclerosis. The aim of this article is to review recent findings on bone marrow-derived progenitor cells obtained from animal models and clinical trials. |
| first_indexed | 2024-12-10T20:16:45Z |
| format | Article |
| id | doaj.art-c6a6098ee3344cc69203e8a5d1bc7123 |
| institution | Directory Open Access Journal |
| issn | 1873-9598 |
| language | English |
| last_indexed | 2024-12-10T20:16:45Z |
| publishDate | 2007-03-01 |
| publisher | Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) |
| record_format | Article |
| series | International Journal of Gerontology |
| spelling | doaj.art-c6a6098ee3344cc69203e8a5d1bc71232022-12-22T01:35:11ZengTaiwan Society of Geriatric Emergency and Critical Medicine (TSGECM)International Journal of Gerontology1873-95982007-03-0111102110.1016/S1873-9598(08)70019-XTherapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad?Kimie Tanaka0Masataka Sata1Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo, JapanDepartment of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo, JapanAccumulating evidence suggests that bone marrow-derived progenitor cells contribute to vascular healing and remodeling under physiologic and pathologic conditions. Although there is growing enthusiasm for therapeutic and diagnostic application of bone marrow-derived progenitors, there is a possibility that transplanted precursors or bone marrow cells may participate in the pathogenesis of unexpected diseases such as cancer, retinopathy, and atherosclerosis. The aim of this article is to review recent findings on bone marrow-derived progenitor cells obtained from animal models and clinical trials.http://www.sciencedirect.com/science/article/pii/S187395980870019Xatherosclerosisendothelial cellsprogenitorssmooth muscle cellsstem cell |
| spellingShingle | Kimie Tanaka Masataka Sata Therapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad? International Journal of Gerontology atherosclerosis endothelial cells progenitors smooth muscle cells stem cell |
| title | Therapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad? |
| title_full | Therapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad? |
| title_fullStr | Therapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad? |
| title_full_unstemmed | Therapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad? |
| title_short | Therapeutic Application of Bone Marrow-derived Progenitor Cells for Vascular Diseases: Magicbullets Having the Good Without the Bad? |
| title_sort | therapeutic application of bone marrow derived progenitor cells for vascular diseases magicbullets having the good without the bad |
| topic | atherosclerosis endothelial cells progenitors smooth muscle cells stem cell |
| url | http://www.sciencedirect.com/science/article/pii/S187395980870019X |
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