Paternal preconceptional supplementation of n‐3 polyunsaturated fatty acids alleviates offspring nonalcoholic fatty liver disease in high‐fat diet‐induced obese mice

Paternal preconceptional supplementation of n‐3 polyunsaturated fatty acids alleviates offspring nonalcoholic fatty liver disease in high‐fat diet‐induced obese mice

Abstract Exposure to nutritional or environmental factors in early life determines susceptibility to nonalcoholic fatty liver disease (NAFLD). The effect of paternal preconceptional n‐3 polyunsaturated fatty acids (n‐3 PUFAs) on offspring NAFLD development remains unknown. Herein, a mouse model that...

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Bibliographic Details
Main Authors: Qiaoyu Shi, Xiuqin Fan, Mengyi Yang, Tiantian Tang, Rui Wang, Ping Li, Kemin Qi
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Food Frontiers
Subjects:
brown adipose tissue
gut microbiota
n‐3 fatty acids
nonalcoholic fatty liver disease
paternal programming
Online Access:https://doi.org/10.1002/fft2.339

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