Comparision of Tuberculin Skin Test and RD1-ELISPOT Assay in Health Care Workers

Health care worker (HCW)s carry a higher burden of tuberculosis infection than that of the general public. In this study we compared tuberculin skin test (TST) with RD1-ELISPOT assay in detection of tuberculosis infection in HCWs. Twenty HCWs were investigated, among them 12 had a positive and eight...

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Bibliographic Details
Main Authors: Ahmet SOYSAL, Ayşegül YAĞCI, Mustafa BAKIR
Format: Article
Language:English
Published: Bilimsel Tip Yayinevi 2005-09-01
Series:Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
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Online Access:http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2005-10-3-139-143.pdf
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Summary:Health care worker (HCW)s carry a higher burden of tuberculosis infection than that of the general public. In this study we compared tuberculin skin test (TST) with RD1-ELISPOT assay in detection of tuberculosis infection in HCWs. Twenty HCWs were investigated, among them 12 had a positive and eight had a negative TST result. RD1-ELISPOT assay was negative in all TST negative ones. Among TST positive ones, two subjects had a negative RD1-ELISPOT assay result. Use of RD1-ELISPOT assay in detection of tuberculosis infection may avoid unnecessary antimicrobial prophylaxis.
ISSN:1300-932X
1300-932X