The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model.

The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model.

Neurodegenerative diseases provoke robust immunological reactions in the central nervous system (CNS), which further deteriorate the neural tissue damage. We hypothesized that the expression levels of indoleamine 2,3-dioxygenase (IDO), an enzyme that has potent immune suppressive activities, in neur...

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Detalhes bibliográficos
Principais autores: Young Eun Lee, Jaeyeol An, Kee-Hang Lee, Sung Su Kim, Hye Jin Song, Heejang Pyeon, Hyun Nam, Kyeongjin Kang, Kyeung Min Joo
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2015-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4670164?pdf=render

Internet

http://europepmc.org/articles/PMC4670164?pdf=render

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