Study the role CoQ10 in improvement of reproductionefficiency in male wister rats

The current study was carried in physiology and pharmacology department at college of veterinary medicine, Al-Qadiysia University. The aim of this study was clarified the effect of Coenzyme Q10 in improvement of reproductive efficiency in male Wister rats after exposed to oxidative stress by lead a...

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Main Authors: Shaymaa Z. Al-Rumaidh, Sanaa T. Jawed, Hussain A. Hussain
Format: Article
Language:English
Published: Faculty of Veterinary Medicine, University of Kufa 2016-10-01
Series:Kufa Journal for Veterinary Medical Sciences
Subjects:
Online Access:https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4274
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author Shaymaa Z. Al-Rumaidh
Sanaa T. Jawed
Hussain A. Hussain
author_facet Shaymaa Z. Al-Rumaidh
Sanaa T. Jawed
Hussain A. Hussain
author_sort Shaymaa Z. Al-Rumaidh
collection DOAJ
description The current study was carried in physiology and pharmacology department at college of veterinary medicine, Al-Qadiysia University. The aim of this study was clarified the effect of Coenzyme Q10 in improvement of reproductive efficiency in male Wister rats after exposed to oxidative stress by lead acetate.40 male rats at 60 days old with 135±11gm in weight were divided into four equal groups, The first group was given distilled water with orally gavage for 60 days as control group (C).The second group (T1)wasgiven CoQ10 (200mg/kg/b.w)for 60 days , while the third group (T2) given lead acetate (10mg/kg/b.w) for 60 days. The forth(T4) group was gives lead acetate (10mg/kg/b.w) for 30 days then given CoQ10 for 30 days. At 60 days of experiment all animals were sacrified, sample of testis taken for measure the gene expression of(CYP17 and CPY11), gene expression results were revealed that there is up regulation (p≤0.05) in T1 compared with T2.
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spelling doaj.art-c6abf1553ea44bbc9622580bf3e1aa752024-01-06T10:17:28ZengFaculty of Veterinary Medicine, University of KufaKufa Journal for Veterinary Medical Sciences2077-97982959-84782016-10-0171B10.36326/kjvs/2016/v7i1B4274Study the role CoQ10 in improvement of reproductionefficiency in male wister ratsShaymaa Z. Al-RumaidhSanaa T. JawedHussain A. Hussain The current study was carried in physiology and pharmacology department at college of veterinary medicine, Al-Qadiysia University. The aim of this study was clarified the effect of Coenzyme Q10 in improvement of reproductive efficiency in male Wister rats after exposed to oxidative stress by lead acetate.40 male rats at 60 days old with 135±11gm in weight were divided into four equal groups, The first group was given distilled water with orally gavage for 60 days as control group (C).The second group (T1)wasgiven CoQ10 (200mg/kg/b.w)for 60 days , while the third group (T2) given lead acetate (10mg/kg/b.w) for 60 days. The forth(T4) group was gives lead acetate (10mg/kg/b.w) for 30 days then given CoQ10 for 30 days. At 60 days of experiment all animals were sacrified, sample of testis taken for measure the gene expression of(CYP17 and CPY11), gene expression results were revealed that there is up regulation (p≤0.05) in T1 compared with T2. https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4274CoQ10CYP17 and CPY11 geneqRT-PC
spellingShingle Shaymaa Z. Al-Rumaidh
Sanaa T. Jawed
Hussain A. Hussain
Study the role CoQ10 in improvement of reproductionefficiency in male wister rats
Kufa Journal for Veterinary Medical Sciences
CoQ10
CYP17 and CPY11 gene
qRT-PC
title Study the role CoQ10 in improvement of reproductionefficiency in male wister rats
title_full Study the role CoQ10 in improvement of reproductionefficiency in male wister rats
title_fullStr Study the role CoQ10 in improvement of reproductionefficiency in male wister rats
title_full_unstemmed Study the role CoQ10 in improvement of reproductionefficiency in male wister rats
title_short Study the role CoQ10 in improvement of reproductionefficiency in male wister rats
title_sort study the role coq10 in improvement of reproductionefficiency in male wister rats
topic CoQ10
CYP17 and CPY11 gene
qRT-PC
url https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4274
work_keys_str_mv AT shaymaazalrumaidh studytherolecoq10inimprovementofreproductionefficiencyinmalewisterrats
AT sanaatjawed studytherolecoq10inimprovementofreproductionefficiencyinmalewisterrats
AT hussainahussain studytherolecoq10inimprovementofreproductionefficiencyinmalewisterrats