Study the role CoQ10 in improvement of reproductionefficiency in male wister rats
The current study was carried in physiology and pharmacology department at college of veterinary medicine, Al-Qadiysia University. The aim of this study was clarified the effect of Coenzyme Q10 in improvement of reproductive efficiency in male Wister rats after exposed to oxidative stress by lead a...
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Format: | Article |
Language: | English |
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Faculty of Veterinary Medicine, University of Kufa
2016-10-01
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Series: | Kufa Journal for Veterinary Medical Sciences |
Subjects: | |
Online Access: | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4274 |
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author | Shaymaa Z. Al-Rumaidh Sanaa T. Jawed Hussain A. Hussain |
author_facet | Shaymaa Z. Al-Rumaidh Sanaa T. Jawed Hussain A. Hussain |
author_sort | Shaymaa Z. Al-Rumaidh |
collection | DOAJ |
description |
The current study was carried in physiology and pharmacology department at college of veterinary medicine, Al-Qadiysia University. The aim of this study was clarified the effect of Coenzyme Q10 in improvement of reproductive efficiency in male Wister rats after exposed to oxidative stress by lead acetate.40 male rats at 60 days old with 135±11gm in weight were divided into four equal groups, The first group was given distilled water with orally gavage for 60 days as control group (C).The second group (T1)wasgiven CoQ10 (200mg/kg/b.w)for 60 days , while the third group (T2) given lead acetate (10mg/kg/b.w) for 60 days. The forth(T4) group was gives lead acetate (10mg/kg/b.w) for 30 days then given CoQ10 for 30 days. At 60 days of experiment all animals were sacrified, sample of testis taken for measure the gene expression of(CYP17 and CPY11), gene expression results were revealed that there is up regulation (p≤0.05) in T1 compared with T2.
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first_indexed | 2024-03-08T16:29:37Z |
format | Article |
id | doaj.art-c6abf1553ea44bbc9622580bf3e1aa75 |
institution | Directory Open Access Journal |
issn | 2077-9798 2959-8478 |
language | English |
last_indexed | 2024-03-08T16:29:37Z |
publishDate | 2016-10-01 |
publisher | Faculty of Veterinary Medicine, University of Kufa |
record_format | Article |
series | Kufa Journal for Veterinary Medical Sciences |
spelling | doaj.art-c6abf1553ea44bbc9622580bf3e1aa752024-01-06T10:17:28ZengFaculty of Veterinary Medicine, University of KufaKufa Journal for Veterinary Medical Sciences2077-97982959-84782016-10-0171B10.36326/kjvs/2016/v7i1B4274Study the role CoQ10 in improvement of reproductionefficiency in male wister ratsShaymaa Z. Al-RumaidhSanaa T. JawedHussain A. Hussain The current study was carried in physiology and pharmacology department at college of veterinary medicine, Al-Qadiysia University. The aim of this study was clarified the effect of Coenzyme Q10 in improvement of reproductive efficiency in male Wister rats after exposed to oxidative stress by lead acetate.40 male rats at 60 days old with 135±11gm in weight were divided into four equal groups, The first group was given distilled water with orally gavage for 60 days as control group (C).The second group (T1)wasgiven CoQ10 (200mg/kg/b.w)for 60 days , while the third group (T2) given lead acetate (10mg/kg/b.w) for 60 days. The forth(T4) group was gives lead acetate (10mg/kg/b.w) for 30 days then given CoQ10 for 30 days. At 60 days of experiment all animals were sacrified, sample of testis taken for measure the gene expression of(CYP17 and CPY11), gene expression results were revealed that there is up regulation (p≤0.05) in T1 compared with T2. https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4274CoQ10CYP17 and CPY11 geneqRT-PC |
spellingShingle | Shaymaa Z. Al-Rumaidh Sanaa T. Jawed Hussain A. Hussain Study the role CoQ10 in improvement of reproductionefficiency in male wister rats Kufa Journal for Veterinary Medical Sciences CoQ10 CYP17 and CPY11 gene qRT-PC |
title | Study the role CoQ10 in improvement of reproductionefficiency in male wister rats |
title_full | Study the role CoQ10 in improvement of reproductionefficiency in male wister rats |
title_fullStr | Study the role CoQ10 in improvement of reproductionefficiency in male wister rats |
title_full_unstemmed | Study the role CoQ10 in improvement of reproductionefficiency in male wister rats |
title_short | Study the role CoQ10 in improvement of reproductionefficiency in male wister rats |
title_sort | study the role coq10 in improvement of reproductionefficiency in male wister rats |
topic | CoQ10 CYP17 and CPY11 gene qRT-PC |
url | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4274 |
work_keys_str_mv | AT shaymaazalrumaidh studytherolecoq10inimprovementofreproductionefficiencyinmalewisterrats AT sanaatjawed studytherolecoq10inimprovementofreproductionefficiencyinmalewisterrats AT hussainahussain studytherolecoq10inimprovementofreproductionefficiencyinmalewisterrats |