Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study

There are some reports about the neurological manifestations and complications of COVID-19. We present neurological manifestations in 6 hospitalized patients with COVID-19. The patients presented with common symptoms of COVID-19 along with common findings from high-resolution computed tomography (HR...

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Main Authors: Zamanian M. H., Janbakhsh A., Mansouri F., Sayad B., Afsharian M., Vaziri S., Mahdavian B., Afshar Z. M., Miladi R., Shirvani M., Noori M., Salimi M., Babazadeh A., Ebrahimpour S.
Format: Article
Language:English
Published: Sciendo 2021-10-01
Series:Acta Medica Bulgarica
Subjects:
Online Access:https://doi.org/10.2478/amb-2021-0035
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author Zamanian M. H.
Janbakhsh A.
Mansouri F.
Sayad B.
Afsharian M.
Vaziri S.
Mahdavian B.
Afshar Z. M.
Miladi R.
Shirvani M.
Noori M.
Salimi M.
Babazadeh A.
Ebrahimpour S.
author_facet Zamanian M. H.
Janbakhsh A.
Mansouri F.
Sayad B.
Afsharian M.
Vaziri S.
Mahdavian B.
Afshar Z. M.
Miladi R.
Shirvani M.
Noori M.
Salimi M.
Babazadeh A.
Ebrahimpour S.
author_sort Zamanian M. H.
collection DOAJ
description There are some reports about the neurological manifestations and complications of COVID-19. We present neurological manifestations in 6 hospitalized patients with COVID-19. The patients presented with common symptoms of COVID-19 along with common findings from high-resolution computed tomography (HRCT) scan such as ground-glass opacities (GGOs). Though, RT-PCR testing of SARS-CoV-2 was negative for all 6 cases. In the current report, acute cerebrovascular diseases affected older patients, while dementia, seizure and encephalopathy affected younger ones. Three of the 6 patients had proven strokes based on their neuroimaging. Four of the 6 patients had high d-dimer levels. Two of the cases experienced convulsion. The third patient presented with typical symptoms and signs of neuroleptic malignant syndrome. The sixth case was interesting for transient dementia. Unfortunately, four out of six patients died. The recent case series report the association between neurological involvements and COVID-19 infection. Clinicians should be alert of the neurologic symptoms in the setting of COVID-19, which might even be the first presentations of this infection.
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spelling doaj.art-c6acd5ba53cc4c1782cd7bc6c9ca6fbb2023-09-18T06:32:58ZengSciendoActa Medica Bulgarica2719-53842021-10-01483414510.2478/amb-2021-0035Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series StudyZamanian M. H.0Janbakhsh A.1Mansouri F.2Sayad B.3Afsharian M.4Vaziri S.5Mahdavian B.6Afshar Z. M.7Miladi R.8Shirvani M.9Noori M.10Salimi M.11Babazadeh A.12Ebrahimpour S.13Infectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases Research Center, Kermanshah University of Medical Sciences – Kermanshah, IranClinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences – Kermanshah, IranDepartment of Internal Medicine, Kermanshah University of Medical Sciences – Kermanshah, IranInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences – Babol, I.R. IranInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences – Babol, I.R. IranThere are some reports about the neurological manifestations and complications of COVID-19. We present neurological manifestations in 6 hospitalized patients with COVID-19. The patients presented with common symptoms of COVID-19 along with common findings from high-resolution computed tomography (HRCT) scan such as ground-glass opacities (GGOs). Though, RT-PCR testing of SARS-CoV-2 was negative for all 6 cases. In the current report, acute cerebrovascular diseases affected older patients, while dementia, seizure and encephalopathy affected younger ones. Three of the 6 patients had proven strokes based on their neuroimaging. Four of the 6 patients had high d-dimer levels. Two of the cases experienced convulsion. The third patient presented with typical symptoms and signs of neuroleptic malignant syndrome. The sixth case was interesting for transient dementia. Unfortunately, four out of six patients died. The recent case series report the association between neurological involvements and COVID-19 infection. Clinicians should be alert of the neurologic symptoms in the setting of COVID-19, which might even be the first presentations of this infection.https://doi.org/10.2478/amb-2021-0035covid-19neurologic manifestationscomplicationcase series
spellingShingle Zamanian M. H.
Janbakhsh A.
Mansouri F.
Sayad B.
Afsharian M.
Vaziri S.
Mahdavian B.
Afshar Z. M.
Miladi R.
Shirvani M.
Noori M.
Salimi M.
Babazadeh A.
Ebrahimpour S.
Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study
Acta Medica Bulgarica
covid-19
neurologic manifestations
complication
case series
title Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study
title_full Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study
title_fullStr Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study
title_full_unstemmed Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study
title_short Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study
title_sort neurological manifestations of hospitalized patients with covid 19 a case series study
topic covid-19
neurologic manifestations
complication
case series
url https://doi.org/10.2478/amb-2021-0035
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