Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus

Background: Assessing the health-related quality of life in patients with type 2 diabetes mellitus is important for evaluation of treatment outcome. The purpose of this study was to evaluate the health-related quality of life in type 2 diabetes mellitus patients and its related factors in Yazd. Meth...

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Main Authors: Forouzan Zare, Hosein Ameri, Farzan Madadizadeh, Mohammad Reza Aghaei
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/2050312120965314
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author Forouzan Zare
Hosein Ameri
Farzan Madadizadeh
Mohammad Reza Aghaei
author_facet Forouzan Zare
Hosein Ameri
Farzan Madadizadeh
Mohammad Reza Aghaei
author_sort Forouzan Zare
collection DOAJ
description Background: Assessing the health-related quality of life in patients with type 2 diabetes mellitus is important for evaluation of treatment outcome. The purpose of this study was to evaluate the health-related quality of life in type 2 diabetes mellitus patients and its related factors in Yazd. Methods: Data were gathered by using the EuroQoL-five-dimension-5 level instrument as well as using medical records of 734 outpatients with type 2 diabetes mellitus who were referred to the largest governmental diabetes center in South of Iran, Yazd province. When appropriate, the Kruskal–Wallis test or the Wilcoxon test was used to test the difference in the health-related quality-of-life scores in each factor. Finally, the adjusted limited dependent variable mixture model was developed to investigate factors associated with health-related quality-of-life scores. Results: The mean and median of the EuroQoL-five-dimension-5 level index values of 717 patients who completed the questionnaires were 0.75 ± 0.006 and 0.72 ± 0.20, respectively, and those of the Visual Analogue Scale scores were 69.25 ± 0.63 and 75 ± 30, respectively. The mean scores for health-related quality of life were significantly higher for employed, educated, single, and male patients, as well as patients without comorbidities, diabetes-related complications, and hemoglobin A1c level >7%. Adjusted limited dependent variable mixture model showed that gender, age, marital status, and diabetes-related complications are significant independent predictors of EuroQoL-five-dimension-5 level index value. Conclusion: The mean scores for health-related quality of life in patients with type 2 diabetes mellitus were moderate in this study, and this finding is consistent with health-related quality-of-life scores reported in other studies conducted in the Middle East region. Therefore, health-related quality of life should be the most important consideration in the management of patients. In parallel, some factors, especially gender, should be considered to improve health-related quality of life.
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spelling doaj.art-c6b2ca8e56c94c839453443d8244a3412022-12-22T00:23:49ZengSAGE PublishingSAGE Open Medicine2050-31212020-10-01810.1177/2050312120965314Health-related quality of life and its associated factors in patients with type 2 diabetes mellitusForouzan Zare0Hosein Ameri1Farzan Madadizadeh2Mohammad Reza Aghaei3Department of Health Technology Assessment, Shahid Sadoughi University of Medical Sciences, Yazd, IranDepartment of Health Technology Assessment, Shahid Sadoughi University of Medical Sciences, Yazd, IranDepartment of Epidemiology and Biostatistics, Shahid Sadoughi University of Medical Sciences, Yazd, IranYazd Diabetic Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranBackground: Assessing the health-related quality of life in patients with type 2 diabetes mellitus is important for evaluation of treatment outcome. The purpose of this study was to evaluate the health-related quality of life in type 2 diabetes mellitus patients and its related factors in Yazd. Methods: Data were gathered by using the EuroQoL-five-dimension-5 level instrument as well as using medical records of 734 outpatients with type 2 diabetes mellitus who were referred to the largest governmental diabetes center in South of Iran, Yazd province. When appropriate, the Kruskal–Wallis test or the Wilcoxon test was used to test the difference in the health-related quality-of-life scores in each factor. Finally, the adjusted limited dependent variable mixture model was developed to investigate factors associated with health-related quality-of-life scores. Results: The mean and median of the EuroQoL-five-dimension-5 level index values of 717 patients who completed the questionnaires were 0.75 ± 0.006 and 0.72 ± 0.20, respectively, and those of the Visual Analogue Scale scores were 69.25 ± 0.63 and 75 ± 30, respectively. The mean scores for health-related quality of life were significantly higher for employed, educated, single, and male patients, as well as patients without comorbidities, diabetes-related complications, and hemoglobin A1c level >7%. Adjusted limited dependent variable mixture model showed that gender, age, marital status, and diabetes-related complications are significant independent predictors of EuroQoL-five-dimension-5 level index value. Conclusion: The mean scores for health-related quality of life in patients with type 2 diabetes mellitus were moderate in this study, and this finding is consistent with health-related quality-of-life scores reported in other studies conducted in the Middle East region. Therefore, health-related quality of life should be the most important consideration in the management of patients. In parallel, some factors, especially gender, should be considered to improve health-related quality of life.https://doi.org/10.1177/2050312120965314
spellingShingle Forouzan Zare
Hosein Ameri
Farzan Madadizadeh
Mohammad Reza Aghaei
Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus
SAGE Open Medicine
title Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus
title_full Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus
title_fullStr Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus
title_full_unstemmed Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus
title_short Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus
title_sort health related quality of life and its associated factors in patients with type 2 diabetes mellitus
url https://doi.org/10.1177/2050312120965314
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