Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY
Abstract Background The prevalence of dog erythrocyte antigen (DEA 1) in canine population is approximately 40–60%. Often data are limited to a small number of breeds and/or dogs. The aims of this study were to evaluate frequency of DEA 1 in a large population of purebred and mongrel dogs including...
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| Format: | Article |
| Language: | English |
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BMC
2017-11-01
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| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12917-017-1286-y |
| _version_ | 1819147157368733696 |
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| author | E. Carli A. Carminato S. Ravagnan K. Capello M. T. Antognoni A. Miglio T. Furlanello D. Proverbio E. Spada A. Stefani F. Mutinelli M. Vascellari |
| author_facet | E. Carli A. Carminato S. Ravagnan K. Capello M. T. Antognoni A. Miglio T. Furlanello D. Proverbio E. Spada A. Stefani F. Mutinelli M. Vascellari |
| author_sort | E. Carli |
| collection | DOAJ |
| description | Abstract Background The prevalence of dog erythrocyte antigen (DEA 1) in canine population is approximately 40–60%. Often data are limited to a small number of breeds and/or dogs. The aims of this study were to evaluate frequency of DEA 1 in a large population of purebred and mongrel dogs including Italian native breeds and to recognize a possible association between DEA 1 and breed, sex, and genetic and phenotypical/functional classifications of breeds. Frequencies of DEA 1 blood group collected from screened/enrolled blood donors and from healthy and sick dogs were retrospectively evaluated. The breed and the sex were recorded when available. DEA 1 blood typing was assessed by immunocromatographic test on K3EDTA blood samples. The prevalence of DEA 1 antigen was statistically related to breed, gender, Fédération Cynologique Internationale (FCI) and genotypic grouping. Results Sixty-two per cent dogs resulted DEA 1+ and 38% DEA 1-. DEA 1- was statistically associated with Dogo Argentino, Dobermann, German Shepherd, Boxer, Corso dogs, the molossian dogs, the FCI group 1, 2 and 3 and the genetic groups “working dogs” and “mastiff”. DEA 1+ was statistically associated with Rottweiler, Briquet Griffon Vendéen, Bernese mountain dog, Golden Retriever, the hunting breeds, the FCI group 4, 6, 7 and 8 and the genetic groups “scent hounds” and “retrievers”. No gender association was observed. Conclusions Data obtained by this work may be clinically useful to drive blood donor enrollment and selection among different breeds. |
| first_indexed | 2024-12-22T13:25:21Z |
| format | Article |
| id | doaj.art-c6b51cb3ebcc43d8afa9df22eb398770 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-22T13:25:21Z |
| publishDate | 2017-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-c6b51cb3ebcc43d8afa9df22eb3987702022-12-21T18:24:21ZengBMCBMC Veterinary Research1746-61482017-11-011311610.1186/s12917-017-1286-yFrequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALYE. Carli0A. Carminato1S. Ravagnan2K. Capello3M. T. Antognoni4A. Miglio5T. Furlanello6D. Proverbio7E. Spada8A. Stefani9F. Mutinelli10M. Vascellari11Canine Blood Bank, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Viale dell’Università 10Veterinary Laboratory “Vetlab”Canine Blood Bank, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Viale dell’Università 10Canine Blood Bank, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Viale dell’Università 10Department of Veterinary Medicine, Unit of Transfusion MedicineDepartment of Veterinary Medicine, Unit of Transfusion MedicineVeterinary laboratory “San Marco”Department of Veterinary Medicine,Veterinary Transfusion Research Laboratory (REVLab), University of MilanDepartment of Veterinary Medicine,Veterinary Transfusion Research Laboratory (REVLab), University of MilanCanine Blood Bank, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Viale dell’Università 10Canine Blood Bank, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Viale dell’Università 10Canine Blood Bank, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Viale dell’Università 10Abstract Background The prevalence of dog erythrocyte antigen (DEA 1) in canine population is approximately 40–60%. Often data are limited to a small number of breeds and/or dogs. The aims of this study were to evaluate frequency of DEA 1 in a large population of purebred and mongrel dogs including Italian native breeds and to recognize a possible association between DEA 1 and breed, sex, and genetic and phenotypical/functional classifications of breeds. Frequencies of DEA 1 blood group collected from screened/enrolled blood donors and from healthy and sick dogs were retrospectively evaluated. The breed and the sex were recorded when available. DEA 1 blood typing was assessed by immunocromatographic test on K3EDTA blood samples. The prevalence of DEA 1 antigen was statistically related to breed, gender, Fédération Cynologique Internationale (FCI) and genotypic grouping. Results Sixty-two per cent dogs resulted DEA 1+ and 38% DEA 1-. DEA 1- was statistically associated with Dogo Argentino, Dobermann, German Shepherd, Boxer, Corso dogs, the molossian dogs, the FCI group 1, 2 and 3 and the genetic groups “working dogs” and “mastiff”. DEA 1+ was statistically associated with Rottweiler, Briquet Griffon Vendéen, Bernese mountain dog, Golden Retriever, the hunting breeds, the FCI group 4, 6, 7 and 8 and the genetic groups “scent hounds” and “retrievers”. No gender association was observed. Conclusions Data obtained by this work may be clinically useful to drive blood donor enrollment and selection among different breeds.http://link.springer.com/article/10.1186/s12917-017-1286-yDEA 1 antigenDogTransfusion |
| spellingShingle | E. Carli A. Carminato S. Ravagnan K. Capello M. T. Antognoni A. Miglio T. Furlanello D. Proverbio E. Spada A. Stefani F. Mutinelli M. Vascellari Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY BMC Veterinary Research DEA 1 antigen Dog Transfusion |
| title | Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY |
| title_full | Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY |
| title_fullStr | Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY |
| title_full_unstemmed | Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY |
| title_short | Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY |
| title_sort | frequency of dea 1 antigen in 1037 mongrel and purebreed dogs in italy |
| topic | DEA 1 antigen Dog Transfusion |
| url | http://link.springer.com/article/10.1186/s12917-017-1286-y |
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