Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis

Dysregulation in mitophagy, in addition to contributing to imbalance in the mitochondrial dynamic, has been implicated in the development of renal fibrosis and progression of chronic kidney disease (CKD). However, the current understanding of the precise mechanisms behind the pathogenic loss of mito...

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Bibliographic Details
Main Authors: Yeo Min Yoon, Gyeongyun Go, Sungtae Yoon, Ji Ho Lim, Gaeun Lee, Jun Hee Lee, Sang Hun Lee
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/7/1682