The Effect of Cholesterol on the Long-Range Network of Interactions Established among Sea Anemone Sticholysin II Residues at the Water-Membrane Interface

The Effect of Cholesterol on the Long-Range Network of Interactions Established among Sea Anemone Sticholysin II Residues at the Water-Membrane Interface

Actinoporins are α-pore forming proteins with therapeutic potential, produced by sea anemones. Sticholysin II (StnII) from Stichodactyla helianthus is one of its most extensively characterized members. These proteins remain stably folded in water, but upon interaction with lipid bilayers, they oligo...

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Bibliographic Details
Main Authors: Sara García-Linares, Ida Alm, Terhi Maula, José G. Gavilanes, Johan Peter Slotte, Álvaro Martínez-del-Pozo
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Marine Drugs
Subjects:
actinoporin
equinatoxin
sphingomyelin
pore-forming toxin
Online Access:http://www.mdpi.com/1660-3397/13/4/1647

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