Evaluation of flurazepam and placebo on sleep disorders in childhood
The clinically observed results in 40 patients, from 1 to 15 years old, presenting sleep disturbances, in a comparative and statistically approached study of flurazepam 15mg daily against placebo, are reported. Placebo was administered, followed by the drug, during 14 days each. The chief complaints...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
1982-03-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1982000100001&lng=en&tlng=en |
| _version_ | 1818535213505970176 |
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| author | Rubens Reimão Antonio B. Lefévre |
| author_facet | Rubens Reimão Antonio B. Lefévre |
| author_sort | Rubens Reimão |
| collection | DOAJ |
| description | The clinically observed results in 40 patients, from 1 to 15 years old, presenting sleep disturbances, in a comparative and statistically approached study of flurazepam 15mg daily against placebo, are reported. Placebo was administered, followed by the drug, during 14 days each. The chief complaints were sleepwalking, sleep-talking, sleep terror, sleep-related bruxism, sleep-related headbanging, insomnia and excessive movements during sleep. A significant effect of flurazepam on sleepwalking, sleep-talking, bruxism, sleep terror and excessive movement during sleep, was observed. The insomniac and headbanging patients were not enough for statistical analysis. Flurazepam side effects were excessive drowsiness during daytime in 3 cases; irritability, 3 cases; nausea and vomiting, 2 cases, and were not correlated with age. Placebo side effects were similar, except for nausea and vomiting which were not observed. It was necessary to discontinue flurazepam in 2 cases, because of excessive drowsiness during daytime, which did not improve when reducing the dose. |
| first_indexed | 2024-12-11T18:21:50Z |
| format | Article |
| id | doaj.art-c6c93429e27740ea975797b2b032ab6e |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-11T18:21:50Z |
| publishDate | 1982-03-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-c6c93429e27740ea975797b2b032ab6e2022-12-22T00:55:13ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42271982-03-0140111310.1590/S0004-282X1982000100001S0004-282X1982000100001Evaluation of flurazepam and placebo on sleep disorders in childhoodRubens Reimão0Antonio B. Lefévre1Universidade de São PauloUniversidade de São PauloThe clinically observed results in 40 patients, from 1 to 15 years old, presenting sleep disturbances, in a comparative and statistically approached study of flurazepam 15mg daily against placebo, are reported. Placebo was administered, followed by the drug, during 14 days each. The chief complaints were sleepwalking, sleep-talking, sleep terror, sleep-related bruxism, sleep-related headbanging, insomnia and excessive movements during sleep. A significant effect of flurazepam on sleepwalking, sleep-talking, bruxism, sleep terror and excessive movement during sleep, was observed. The insomniac and headbanging patients were not enough for statistical analysis. Flurazepam side effects were excessive drowsiness during daytime in 3 cases; irritability, 3 cases; nausea and vomiting, 2 cases, and were not correlated with age. Placebo side effects were similar, except for nausea and vomiting which were not observed. It was necessary to discontinue flurazepam in 2 cases, because of excessive drowsiness during daytime, which did not improve when reducing the dose.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1982000100001&lng=en&tlng=en |
| spellingShingle | Rubens Reimão Antonio B. Lefévre Evaluation of flurazepam and placebo on sleep disorders in childhood Arquivos de Neuro-Psiquiatria |
| title | Evaluation of flurazepam and placebo on sleep disorders in childhood |
| title_full | Evaluation of flurazepam and placebo on sleep disorders in childhood |
| title_fullStr | Evaluation of flurazepam and placebo on sleep disorders in childhood |
| title_full_unstemmed | Evaluation of flurazepam and placebo on sleep disorders in childhood |
| title_short | Evaluation of flurazepam and placebo on sleep disorders in childhood |
| title_sort | evaluation of flurazepam and placebo on sleep disorders in childhood |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1982000100001&lng=en&tlng=en |
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