Multiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year period

Background. Cavernous hemangioma is a frequent and the most common, primary, benign tumor of the orbit in adults. It is typically single and unilateral, considered not to recur after having been completely excised. Multiple orbital cavernous hemangiomas without signs of hemangiomatosis are rare. Mul...

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Main Authors: Nagulić Mirjana, Nikolić Igor, Manojlović-Gačić Emilija, Skender-Gazibara Milica
Format: Article
Language:English
Published: Military Health Department, Ministry of Defance, Serbia 2010-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2010/0042-84501006507N.pdf
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author Nagulić Mirjana
Nikolić Igor
Manojlović-Gačić Emilija
Skender-Gazibara Milica
author_facet Nagulić Mirjana
Nikolić Igor
Manojlović-Gačić Emilija
Skender-Gazibara Milica
author_sort Nagulić Mirjana
collection DOAJ
description Background. Cavernous hemangioma is a frequent and the most common, primary, benign tumor of the orbit in adults. It is typically single and unilateral, considered not to recur after having been completely excised. Multiple orbital cavernous hemangiomas without signs of hemangiomatosis are rare. Multiple cavernous hemangiomas may recur after a complete excision and may exist with concurrent systemic tumors. Tumor recurrence is supposed to develop from vasculature that is present already in response to a proliferate stimulus. Case report. A 39-year old female with painless proptosis of the right orbit was found to have four orbital tumors. The first orbitotomy was performed in 1984 by excising four cavernous hemangiomas. Six years later, another, the fifth one cavernous hemangioma was totally excised from the same orbit. Nine years after the first operation, reorbitotomy was performed because of positive radiological and clinical signs of de novo tumor in the orbit. The operation did not confirm the tumorous tissue. The fourth orbitotomy was performed 24 years after the first operation and two cavernous hemangiomas were totally excised. Conclusion. This case show the possibility of cavernous hemangioma recurrence after a previously totally excised tumor, separated more than two decades. A very long follow-up of the patients operated for these benign tumor lesions is recommended.
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spelling doaj.art-c6cf2161ab9f4d45ae2a8cd170b264642022-12-22T02:49:19ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502010-01-0167650751010.2298/VSP1006507NMultiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year periodNagulić MirjanaNikolić IgorManojlović-Gačić EmilijaSkender-Gazibara MilicaBackground. Cavernous hemangioma is a frequent and the most common, primary, benign tumor of the orbit in adults. It is typically single and unilateral, considered not to recur after having been completely excised. Multiple orbital cavernous hemangiomas without signs of hemangiomatosis are rare. Multiple cavernous hemangiomas may recur after a complete excision and may exist with concurrent systemic tumors. Tumor recurrence is supposed to develop from vasculature that is present already in response to a proliferate stimulus. Case report. A 39-year old female with painless proptosis of the right orbit was found to have four orbital tumors. The first orbitotomy was performed in 1984 by excising four cavernous hemangiomas. Six years later, another, the fifth one cavernous hemangioma was totally excised from the same orbit. Nine years after the first operation, reorbitotomy was performed because of positive radiological and clinical signs of de novo tumor in the orbit. The operation did not confirm the tumorous tissue. The fourth orbitotomy was performed 24 years after the first operation and two cavernous hemangiomas were totally excised. Conclusion. This case show the possibility of cavernous hemangioma recurrence after a previously totally excised tumor, separated more than two decades. A very long follow-up of the patients operated for these benign tumor lesions is recommended.http://www.doiserbia.nb.rs/img/doi/0042-8450/2010/0042-84501006507N.pdfhemangiomacavernousorbitneurosurgeryrecurrence
spellingShingle Nagulić Mirjana
Nikolić Igor
Manojlović-Gačić Emilija
Skender-Gazibara Milica
Multiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year period
Vojnosanitetski Pregled
hemangioma
cavernous
orbit
neurosurgery
recurrence
title Multiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year period
title_full Multiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year period
title_fullStr Multiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year period
title_full_unstemmed Multiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year period
title_short Multiple cavernous hemangiomas of the orbit: Separate occurrence within a 24-year period
title_sort multiple cavernous hemangiomas of the orbit separate occurrence within a 24 year period
topic hemangioma
cavernous
orbit
neurosurgery
recurrence
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2010/0042-84501006507N.pdf
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AT nikolicigor multiplecavernoushemangiomasoftheorbitseparateoccurrencewithina24yearperiod
AT manojlovicgacicemilija multiplecavernoushemangiomasoftheorbitseparateoccurrencewithina24yearperiod
AT skendergazibaramilica multiplecavernoushemangiomasoftheorbitseparateoccurrencewithina24yearperiod