Simultaneous consumption of drugs and their implications on cognitive functioning

Introduction: drug abuse is a health problem that affects millions of people around the world. It could be defined as a concurrent condition in which the behavior has the goal of produce a pleasant sensation and reduce the discomfort produced by the interruption of the drug administration. The drug...

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Main Authors: Hugo Sánchez Castillo, Rodrigo Iván Castañeda Garrido, Diana Berenice Paz Trejo, Daniel Soltero de la Rosa, Pável Zárate González
Format: Article
Language:English
Published: Centros de Integración Juvenil A.C. 2018-12-01
Series:Revista Internacional de Investigación en Adicciones
Subjects:
Online Access:http://riiad.org/index.php/riiad/article/view/riiad.2018.2.01
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author Hugo Sánchez Castillo
Rodrigo Iván Castañeda Garrido
Diana Berenice Paz Trejo
Daniel Soltero de la Rosa
Pável Zárate González
author_facet Hugo Sánchez Castillo
Rodrigo Iván Castañeda Garrido
Diana Berenice Paz Trejo
Daniel Soltero de la Rosa
Pável Zárate González
author_sort Hugo Sánchez Castillo
collection DOAJ
description Introduction: drug abuse is a health problem that affects millions of people around the world. It could be defined as a concurrent condition in which the behavior has the goal of produce a pleasant sensation and reduce the discomfort produced by the interruption of the drug administration. The drug retirement produces cognitive alterations, particularly in memory and executive function. Those effects are due to the vulnerability of prefrontal cortex to the drug effects. Poly drug use is defined as the simultaneous intake, or separated in short time lapses, of several drugs. This kind of drug intake has been poorly studied in comparison to other addictions. Objective: to evaluate the effects of poly drug use in three groups of drug consumers evaluated with a neuropsychological battery. Method: thirty-six poly drug consumers were included and eleven non consumers integrated a control group (total sample: 47 subjects). Poly drug consumers were divided in three different groups depending on the kind of drugs consumed. All poly drug users were evaluated with the Neuropsychological battery “Neuropsi Atención y Memoria” and were compared against the performance of control group. Conclusion and discussion: neuropsychological affections were observed, particularly in verbal memory and evocation (both verbal and visuospatial) as well as in abstract attitude and inhibition (p < 0.05). We observed several relapses and readmissions in the rehabilitation center. The findings over inhibition and abstract attitude could explain the poor adhesion to treatment, alterations in everyday life and several relapses.
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spelling doaj.art-c6d03ecddd6c4ee98e9fdddca6873c492022-12-22T01:42:08ZengCentros de Integración Juvenil A.C.Revista Internacional de Investigación en Adicciones2448-573X2448-63962018-12-01421910.28931/riiad.2018.2.01Simultaneous consumption of drugs and their implications on cognitive functioningHugo Sánchez CastilloRodrigo Iván Castañeda GarridoDiana Berenice Paz TrejoDaniel Soltero de la RosaPável Zárate GonzálezIntroduction: drug abuse is a health problem that affects millions of people around the world. It could be defined as a concurrent condition in which the behavior has the goal of produce a pleasant sensation and reduce the discomfort produced by the interruption of the drug administration. The drug retirement produces cognitive alterations, particularly in memory and executive function. Those effects are due to the vulnerability of prefrontal cortex to the drug effects. Poly drug use is defined as the simultaneous intake, or separated in short time lapses, of several drugs. This kind of drug intake has been poorly studied in comparison to other addictions. Objective: to evaluate the effects of poly drug use in three groups of drug consumers evaluated with a neuropsychological battery. Method: thirty-six poly drug consumers were included and eleven non consumers integrated a control group (total sample: 47 subjects). Poly drug consumers were divided in three different groups depending on the kind of drugs consumed. All poly drug users were evaluated with the Neuropsychological battery “Neuropsi Atención y Memoria” and were compared against the performance of control group. Conclusion and discussion: neuropsychological affections were observed, particularly in verbal memory and evocation (both verbal and visuospatial) as well as in abstract attitude and inhibition (p < 0.05). We observed several relapses and readmissions in the rehabilitation center. The findings over inhibition and abstract attitude could explain the poor adhesion to treatment, alterations in everyday life and several relapses.http://riiad.org/index.php/riiad/article/view/riiad.2018.2.01addictionprefrontal cortexneuropsychological assessmentexecutive functionpoly drug consume
spellingShingle Hugo Sánchez Castillo
Rodrigo Iván Castañeda Garrido
Diana Berenice Paz Trejo
Daniel Soltero de la Rosa
Pável Zárate González
Simultaneous consumption of drugs and their implications on cognitive functioning
Revista Internacional de Investigación en Adicciones
addiction
prefrontal cortex
neuropsychological assessment
executive function
poly drug consume
title Simultaneous consumption of drugs and their implications on cognitive functioning
title_full Simultaneous consumption of drugs and their implications on cognitive functioning
title_fullStr Simultaneous consumption of drugs and their implications on cognitive functioning
title_full_unstemmed Simultaneous consumption of drugs and their implications on cognitive functioning
title_short Simultaneous consumption of drugs and their implications on cognitive functioning
title_sort simultaneous consumption of drugs and their implications on cognitive functioning
topic addiction
prefrontal cortex
neuropsychological assessment
executive function
poly drug consume
url http://riiad.org/index.php/riiad/article/view/riiad.2018.2.01
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