Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics
The development of non-invasive optoelectronic technologies for human blood monitoring is one of the important research areas for medicine. A critical analysis of optoelectronic methods of blood research and the micromechanical systems based on them is carried out in this article. A design realizati...
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MDPI AG
2022-12-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/13/12/2241 |
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| author | Ruslan D. Khlynov Victoria A. Ryzhova Sergey N. Yarishev Igor A. Konyakhin Valery V. Korotaev Yuri E. Shelepin Todor S. Djamiykov Marin B. Marinov |
| author_facet | Ruslan D. Khlynov Victoria A. Ryzhova Sergey N. Yarishev Igor A. Konyakhin Valery V. Korotaev Yuri E. Shelepin Todor S. Djamiykov Marin B. Marinov |
| author_sort | Ruslan D. Khlynov |
| collection | DOAJ |
| description | The development of non-invasive optoelectronic technologies for human blood monitoring is one of the important research areas for medicine. A critical analysis of optoelectronic methods of blood research and the micromechanical systems based on them is carried out in this article. A design realization of a polarizing portable system for non-invasive monitoring of hematocrit as one of the basic homeostatic constants of the human body containing information about the microphysical parameters of blood cells has been substantiated. A physical model of polarized radiation conversion in a video information system of laser sensing of a biological research object has been formed. Visual and quantitative differences in the spatial distribution of polarization parameters of the scattered radiation for the states of the body with different hematocrit levels have been revealed. A scheme of a multichannel imaging portable system, based on a smartphone using miniature optical and microelectronic components of information conversion for non-invasive monitoring of microphysical blood parameters, has been created. The system implements the principle of polarimetric blood photometry and a multiparametric analysis of the polarization properties of the laser radiation scattered by blood. The developed portable optoelectronic system, based on a smartphone, can be used for rapid blood diagnostics in disaster medicine and the presence of clinical contraindications to the formation of invasive tests. The proposed polarization-based approach is a promising automated alternative to traditional devices and systems for the research of microphysical blood parameters. |
| first_indexed | 2024-03-09T16:05:31Z |
| format | Article |
| id | doaj.art-c6d0812ef3d44cf2bd0cd66511375afb |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-09T16:05:31Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-c6d0812ef3d44cf2bd0cd66511375afb2023-11-24T16:46:34ZengMDPI AGMicromachines2072-666X2022-12-011312224110.3390/mi13122241Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit DiagnosticsRuslan D. Khlynov0Victoria A. Ryzhova1Sergey N. Yarishev2Igor A. Konyakhin3Valery V. Korotaev4Yuri E. Shelepin5Todor S. Djamiykov6Marin B. Marinov7Applied Optic Centre, ITMO University, Kronverksky Pr. 49, Bldg. A, 197101 St. Petersburg, RussiaSchool of Physics and Engineering, ITMO University, Kronverksky Pr. 49, Bldg. A, 197101 St. Petersburg, RussiaSchool of Physics and Engineering, ITMO University, Kronverksky Pr. 49, Bldg. A, 197101 St. Petersburg, RussiaHigher School of Engineering and Technology, ITMO University, Kronverksky Pr. 49, Bldg. A, 197101 St. Petersburg, RussiaHigher School of Engineering and Technology, ITMO University, Kronverksky Pr. 49, Bldg. A, 197101 St. Petersburg, RussiaPavlov Institute of Physiology, Russian Academy of Sciences, Makarova Embankment, 6, 199034 St. Petersburg, RussiaDepartment of Electronics, Technical University of Sofia, 1756 Sofia, BulgariaDepartment of Electronics, Technical University of Sofia, 1756 Sofia, BulgariaThe development of non-invasive optoelectronic technologies for human blood monitoring is one of the important research areas for medicine. A critical analysis of optoelectronic methods of blood research and the micromechanical systems based on them is carried out in this article. A design realization of a polarizing portable system for non-invasive monitoring of hematocrit as one of the basic homeostatic constants of the human body containing information about the microphysical parameters of blood cells has been substantiated. A physical model of polarized radiation conversion in a video information system of laser sensing of a biological research object has been formed. Visual and quantitative differences in the spatial distribution of polarization parameters of the scattered radiation for the states of the body with different hematocrit levels have been revealed. A scheme of a multichannel imaging portable system, based on a smartphone using miniature optical and microelectronic components of information conversion for non-invasive monitoring of microphysical blood parameters, has been created. The system implements the principle of polarimetric blood photometry and a multiparametric analysis of the polarization properties of the laser radiation scattered by blood. The developed portable optoelectronic system, based on a smartphone, can be used for rapid blood diagnostics in disaster medicine and the presence of clinical contraindications to the formation of invasive tests. The proposed polarization-based approach is a promising automated alternative to traditional devices and systems for the research of microphysical blood parameters.https://www.mdpi.com/2072-666X/13/12/2241bloodnon-invasive monitoringportable polarizing systemoptoelectronic methodsmartphoneStokes vector |
| spellingShingle | Ruslan D. Khlynov Victoria A. Ryzhova Sergey N. Yarishev Igor A. Konyakhin Valery V. Korotaev Yuri E. Shelepin Todor S. Djamiykov Marin B. Marinov Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics Micromachines blood non-invasive monitoring portable polarizing system optoelectronic method smartphone Stokes vector |
| title | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
| title_full | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
| title_fullStr | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
| title_full_unstemmed | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
| title_short | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
| title_sort | analysis of polarization images in the microphysical blood parameters research for the hematocrit diagnostics |
| topic | blood non-invasive monitoring portable polarizing system optoelectronic method smartphone Stokes vector |
| url | https://www.mdpi.com/2072-666X/13/12/2241 |
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