Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal Atomizer
Abstract Introduction Opioid overdose rescue situations are time-critical, high-stress scenarios that frequently require nonmedical first responders or bystanders to intervene and administer naloxone to avoid opioid-induced fatalities. Training nonmedical personnel to respond during such mentally co...
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| Format: | Article |
| Language: | English |
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Adis, Springer Healthcare
2019-03-01
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| Series: | Pain and Therapy |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1007/s40122-019-0118-0 |
| _version_ | 1818158951016955904 |
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| author | Kathryn G. Tippey Mary Yovanoff Larry S. McGrath Peter Sneeringer |
| author_facet | Kathryn G. Tippey Mary Yovanoff Larry S. McGrath Peter Sneeringer |
| author_sort | Kathryn G. Tippey |
| collection | DOAJ |
| description | Abstract Introduction Opioid overdose rescue situations are time-critical, high-stress scenarios that frequently require nonmedical first responders or bystanders to intervene and administer naloxone to avoid opioid-induced fatalities. Training nonmedical personnel to respond during such mentally constraining situations presents the human factors challenge of how best to design a safe and effective lay delivery system. This paper comparatively evaluates the ease of use of two nasal naloxone administration products: NARCAN ® Nasal Spray and a naloxone prefilled syringe with nasal atomizer (PFS-NA). Methods We evaluated the use requirements and usability of NARCAN ® Nasal Spray versus a naloxone PFS-NA using a systems-oriented method. First, we determined the use requirements of different user groups. Next, we focused on constructing a human factors task analysis of both products. Finally, we conducted a comparative risk assessment of the tasks that were different between the two products. Results Inexperienced users, such as nonmedical first responders and bystanders, are at the highest risk of incorrectly administering naloxone, particularly in high-stress emergency opioid overdose situations. The device Preparation and Medication Delivery tasks most differentiate the use of NARCAN ® Nasal Spray and a PFS-NA. The level of task complexity and number of steps within those tasks is substantially greater for a PFS-NA than for the NARCAN ® Nasal Spray. Conclusions NARCAN ® Nasal Spray requires fewer steps and is easier to administer than a naloxone PFS-NA. Thus, using NARCAN ® Nasal Spray should increase the likelihood that nonmedical personnel correctly deliver naloxone in time-critical, high-stress opioid overdose rescue situations. Funding ADAPT Pharma, Inc. |
| first_indexed | 2024-12-11T15:38:14Z |
| format | Article |
| id | doaj.art-c6d3bcc983484ea69881cdd431802cdf |
| institution | Directory Open Access Journal |
| issn | 2193-8237 2193-651X |
| language | English |
| last_indexed | 2024-12-11T15:38:14Z |
| publishDate | 2019-03-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Pain and Therapy |
| spelling | doaj.art-c6d3bcc983484ea69881cdd431802cdf2022-12-22T00:59:53ZengAdis, Springer HealthcarePain and Therapy2193-82372193-651X2019-03-0181899810.1007/s40122-019-0118-0Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal AtomizerKathryn G. Tippey0Mary Yovanoff1Larry S. McGrath2Peter Sneeringer3Design Science ConsultingDesign Science ConsultingDesign Science ConsultingDesign Science ConsultingAbstract Introduction Opioid overdose rescue situations are time-critical, high-stress scenarios that frequently require nonmedical first responders or bystanders to intervene and administer naloxone to avoid opioid-induced fatalities. Training nonmedical personnel to respond during such mentally constraining situations presents the human factors challenge of how best to design a safe and effective lay delivery system. This paper comparatively evaluates the ease of use of two nasal naloxone administration products: NARCAN ® Nasal Spray and a naloxone prefilled syringe with nasal atomizer (PFS-NA). Methods We evaluated the use requirements and usability of NARCAN ® Nasal Spray versus a naloxone PFS-NA using a systems-oriented method. First, we determined the use requirements of different user groups. Next, we focused on constructing a human factors task analysis of both products. Finally, we conducted a comparative risk assessment of the tasks that were different between the two products. Results Inexperienced users, such as nonmedical first responders and bystanders, are at the highest risk of incorrectly administering naloxone, particularly in high-stress emergency opioid overdose situations. The device Preparation and Medication Delivery tasks most differentiate the use of NARCAN ® Nasal Spray and a PFS-NA. The level of task complexity and number of steps within those tasks is substantially greater for a PFS-NA than for the NARCAN ® Nasal Spray. Conclusions NARCAN ® Nasal Spray requires fewer steps and is easier to administer than a naloxone PFS-NA. Thus, using NARCAN ® Nasal Spray should increase the likelihood that nonmedical personnel correctly deliver naloxone in time-critical, high-stress opioid overdose rescue situations. Funding ADAPT Pharma, Inc.http://link.springer.com/article/10.1007/s40122-019-0118-0NaloxoneNARCAN ®OpioidsOverdose |
| spellingShingle | Kathryn G. Tippey Mary Yovanoff Larry S. McGrath Peter Sneeringer Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal Atomizer Pain and Therapy Naloxone NARCAN ® Opioids Overdose |
| title | Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal Atomizer |
| title_full | Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal Atomizer |
| title_fullStr | Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal Atomizer |
| title_full_unstemmed | Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal Atomizer |
| title_short | Comparative Human Factors Evaluation of Two Nasal Naloxone Administration Devices: NARCAN® Nasal Spray and Naloxone Prefilled Syringe with Nasal Atomizer |
| title_sort | comparative human factors evaluation of two nasal naloxone administration devices narcan r nasal spray and naloxone prefilled syringe with nasal atomizer |
| topic | Naloxone NARCAN ® Opioids Overdose |
| url | http://link.springer.com/article/10.1007/s40122-019-0118-0 |
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