Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms

Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms

Exaggerated Type 2 immune responses play critical roles in the pathogenesis of a variety of diseases including asthma, allergy, and pulmonary fibrosis. Recent studies have highlighted the importance of innate type 2 immune responses and innate lymphoid 2 cells (ILC2s) in these disorders. However, th...

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Bibliographic Details
Main Authors: Ashley Hernandez-Gutierrez, Sonoor Majid, Adam Eberle, Ashley Choi, Parand Sorkhdini, Dongqin Yang, Alina Xiaoyu Yang, Carmelissa Norbrun, Chuan Hua He, Chang-min Lee, Chun Geun Lee, Jack A. Elias, Yang Zhou
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-08-01
Series:The Journal of Clinical Investigation
Subjects:
Immunology
Online Access:https://doi.org/10.1172/JCI169583

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