Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children
Purpose: To study the effect of low-dose topical atropine eye drops (0.01%) in slowing myopia progression in school-age children. Methods: This was a prospective randomized controlled study, in children in the age group of 5–15 years, with myopic refractive error (spherical equivalent) between −1.0D...
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Wolters Kluwer Medknow Publications
2024-01-01
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Series: | Journal of Clinical Ophthalmology and Research |
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Online Access: | http://www.jcor.in/article.asp?issn=2320-3897;year=2024;volume=12;issue=1;spage=24;epage=28;aulast=Bansal |
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author | Yashi Bansal Renu Grover Rakesh Chakraborty |
author_facet | Yashi Bansal Renu Grover Rakesh Chakraborty |
author_sort | Yashi Bansal |
collection | DOAJ |
description | Purpose: To study the effect of low-dose topical atropine eye drops (0.01%) in slowing myopia progression in school-age children. Methods: This was a prospective randomized controlled study, in children in the age group of 5–15 years, with myopic refractive error (spherical equivalent) between −1.0D and −5.0D at the time of presentation. A total of 100 patients were studied and randomly divided into two groups of 50 each: the control group and the atropine group. They were followed up 3 monthly for cycloplegic refraction, axial length (AL), pupil size, accommodation, and binocular stereopsis for near for a time period of 2 years. Results: Over a period of 2 years, there was a statistically significant decrease in the progression of myopic spherical equivalent and the AL in the atropine group. The accommodation and binocular stereopsis were comparable in both the groups. There was an average 0.7 mm increase in pupillary size posttreatment in the atropine group. Conclusions: The results of our study indicated that topical atropine (0.01%) is effective in retarding myopia progression at the end of 2 years of treatment. No child experienced allergic reaction, difficulty in reading, or photophobia during the trial period. Thus, atropine eye drops (0.01%) can be considered safe and efficacious in reducing the progression of myopia. |
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format | Article |
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issn | 2320-3897 |
language | English |
last_indexed | 2024-03-07T23:00:31Z |
publishDate | 2024-01-01 |
publisher | Wolters Kluwer Medknow Publications |
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series | Journal of Clinical Ophthalmology and Research |
spelling | doaj.art-c6dd25790dd34b5f9c434e47510595b92024-02-22T14:57:32ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972024-01-01121242810.4103/jcor.jcor_128_23Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age childrenYashi BansalRenu GroverRakesh ChakrabortyPurpose: To study the effect of low-dose topical atropine eye drops (0.01%) in slowing myopia progression in school-age children. Methods: This was a prospective randomized controlled study, in children in the age group of 5–15 years, with myopic refractive error (spherical equivalent) between −1.0D and −5.0D at the time of presentation. A total of 100 patients were studied and randomly divided into two groups of 50 each: the control group and the atropine group. They were followed up 3 monthly for cycloplegic refraction, axial length (AL), pupil size, accommodation, and binocular stereopsis for near for a time period of 2 years. Results: Over a period of 2 years, there was a statistically significant decrease in the progression of myopic spherical equivalent and the AL in the atropine group. The accommodation and binocular stereopsis were comparable in both the groups. There was an average 0.7 mm increase in pupillary size posttreatment in the atropine group. Conclusions: The results of our study indicated that topical atropine (0.01%) is effective in retarding myopia progression at the end of 2 years of treatment. No child experienced allergic reaction, difficulty in reading, or photophobia during the trial period. Thus, atropine eye drops (0.01%) can be considered safe and efficacious in reducing the progression of myopia.http://www.jcor.in/article.asp?issn=2320-3897;year=2024;volume=12;issue=1;spage=24;epage=28;aulast=Bansalaccommodationatropine 0.01% eye dropsaxial lengthcycloplegic refractionmyopianear stereopsispupil sizespherical equivalent |
spellingShingle | Yashi Bansal Renu Grover Rakesh Chakraborty Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children Journal of Clinical Ophthalmology and Research accommodation atropine 0.01% eye drops axial length cycloplegic refraction myopia near stereopsis pupil size spherical equivalent |
title | Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children |
title_full | Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children |
title_fullStr | Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children |
title_full_unstemmed | Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children |
title_short | Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children |
title_sort | efficacy of topical low dose atropine eye drops 0 01 in slowing myopia progression in school age children |
topic | accommodation atropine 0.01% eye drops axial length cycloplegic refraction myopia near stereopsis pupil size spherical equivalent |
url | http://www.jcor.in/article.asp?issn=2320-3897;year=2024;volume=12;issue=1;spage=24;epage=28;aulast=Bansal |
work_keys_str_mv | AT yashibansal efficacyoftopicallowdoseatropineeyedrops001inslowingmyopiaprogressioninschoolagechildren AT renugrover efficacyoftopicallowdoseatropineeyedrops001inslowingmyopiaprogressioninschoolagechildren AT rakeshchakraborty efficacyoftopicallowdoseatropineeyedrops001inslowingmyopiaprogressioninschoolagechildren |