Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children

Purpose: To study the effect of low-dose topical atropine eye drops (0.01%) in slowing myopia progression in school-age children. Methods: This was a prospective randomized controlled study, in children in the age group of 5–15 years, with myopic refractive error (spherical equivalent) between −1.0D...

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Main Authors: Yashi Bansal, Renu Grover, Rakesh Chakraborty
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of Clinical Ophthalmology and Research
Subjects:
Online Access:http://www.jcor.in/article.asp?issn=2320-3897;year=2024;volume=12;issue=1;spage=24;epage=28;aulast=Bansal
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author Yashi Bansal
Renu Grover
Rakesh Chakraborty
author_facet Yashi Bansal
Renu Grover
Rakesh Chakraborty
author_sort Yashi Bansal
collection DOAJ
description Purpose: To study the effect of low-dose topical atropine eye drops (0.01%) in slowing myopia progression in school-age children. Methods: This was a prospective randomized controlled study, in children in the age group of 5–15 years, with myopic refractive error (spherical equivalent) between −1.0D and −5.0D at the time of presentation. A total of 100 patients were studied and randomly divided into two groups of 50 each: the control group and the atropine group. They were followed up 3 monthly for cycloplegic refraction, axial length (AL), pupil size, accommodation, and binocular stereopsis for near for a time period of 2 years. Results: Over a period of 2 years, there was a statistically significant decrease in the progression of myopic spherical equivalent and the AL in the atropine group. The accommodation and binocular stereopsis were comparable in both the groups. There was an average 0.7 mm increase in pupillary size posttreatment in the atropine group. Conclusions: The results of our study indicated that topical atropine (0.01%) is effective in retarding myopia progression at the end of 2 years of treatment. No child experienced allergic reaction, difficulty in reading, or photophobia during the trial period. Thus, atropine eye drops (0.01%) can be considered safe and efficacious in reducing the progression of myopia.
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spelling doaj.art-c6dd25790dd34b5f9c434e47510595b92024-02-22T14:57:32ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972024-01-01121242810.4103/jcor.jcor_128_23Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age childrenYashi BansalRenu GroverRakesh ChakrabortyPurpose: To study the effect of low-dose topical atropine eye drops (0.01%) in slowing myopia progression in school-age children. Methods: This was a prospective randomized controlled study, in children in the age group of 5–15 years, with myopic refractive error (spherical equivalent) between −1.0D and −5.0D at the time of presentation. A total of 100 patients were studied and randomly divided into two groups of 50 each: the control group and the atropine group. They were followed up 3 monthly for cycloplegic refraction, axial length (AL), pupil size, accommodation, and binocular stereopsis for near for a time period of 2 years. Results: Over a period of 2 years, there was a statistically significant decrease in the progression of myopic spherical equivalent and the AL in the atropine group. The accommodation and binocular stereopsis were comparable in both the groups. There was an average 0.7 mm increase in pupillary size posttreatment in the atropine group. Conclusions: The results of our study indicated that topical atropine (0.01%) is effective in retarding myopia progression at the end of 2 years of treatment. No child experienced allergic reaction, difficulty in reading, or photophobia during the trial period. Thus, atropine eye drops (0.01%) can be considered safe and efficacious in reducing the progression of myopia.http://www.jcor.in/article.asp?issn=2320-3897;year=2024;volume=12;issue=1;spage=24;epage=28;aulast=Bansalaccommodationatropine 0.01% eye dropsaxial lengthcycloplegic refractionmyopianear stereopsispupil sizespherical equivalent
spellingShingle Yashi Bansal
Renu Grover
Rakesh Chakraborty
Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children
Journal of Clinical Ophthalmology and Research
accommodation
atropine 0.01% eye drops
axial length
cycloplegic refraction
myopia
near stereopsis
pupil size
spherical equivalent
title Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children
title_full Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children
title_fullStr Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children
title_full_unstemmed Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children
title_short Efficacy of topical low-dose atropine eye drops (0.01%) in slowing myopia progression in school-age children
title_sort efficacy of topical low dose atropine eye drops 0 01 in slowing myopia progression in school age children
topic accommodation
atropine 0.01% eye drops
axial length
cycloplegic refraction
myopia
near stereopsis
pupil size
spherical equivalent
url http://www.jcor.in/article.asp?issn=2320-3897;year=2024;volume=12;issue=1;spage=24;epage=28;aulast=Bansal
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AT renugrover efficacyoftopicallowdoseatropineeyedrops001inslowingmyopiaprogressioninschoolagechildren
AT rakeshchakraborty efficacyoftopicallowdoseatropineeyedrops001inslowingmyopiaprogressioninschoolagechildren