Micro-Sized glucose biosensor based on composite pH sensor

Today's scientific and technical advances have led to significant advances in biosensor technology, leading to widespread use of biosensors in areas such as food technology, the environment, pharmaceuticals and clinical diagnostics, biochemistry, and analytical chemistry. Improvements in the io...

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Main Authors: Özlem Tavukçuoğlu, Derya Bal Altuntaş
Format: Article
Language:English
Published: Pamukkale University 2018-12-01
Series:Pamukkale University Journal of Engineering Sciences
Subjects:
Online Access:https://dergipark.org.tr/tr/pub/pajes/issue/41410/504353
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author Özlem Tavukçuoğlu
Derya Bal Altuntaş
author_facet Özlem Tavukçuoğlu
Derya Bal Altuntaş
author_sort Özlem Tavukçuoğlu
collection DOAJ
description Today's scientific and technical advances have led to significant advances in biosensor technology, leading to widespread use of biosensors in areas such as food technology, the environment, pharmaceuticals and clinical diagnostics, biochemistry, and analytical chemistry. Improvements in the ion-selective sensor technology used in the preparation of potentiometric biosensors and the increase in the number of sensor materials have also accelerated the development of new types of potentiometric biosensors. Thus, in this study, information is given on the development of a new micro sized potentiometric glucose biosensor based on composite pH sensor. Glucose oxidase was immobilized on the composite layer as the biorecognition element. The surface of glucose biosensor based composite pH sensing matrices was first examined for electrochemical elucidation by using cyclic voltammetry and electrochemical impedance spectroscopy. The rate of electron transfer resulted in a stable response behavior of the biosensor and made it a suitable potentiometric sensor for detection of glucose. A linear response in concentration range from 5x10-5 to 1x10-1 mol/L was obtained with a detection limit of 2x10-5 mol/L for the potentiometric detection of glucose. The biosensor exhibited a fast response time (10 s), had good stability, and an extended lifetime.
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spelling doaj.art-c6ddcecd30fb4f888051b9092804fb4b2023-02-15T16:15:05ZengPamukkale UniversityPamukkale University Journal of Engineering Sciences1300-70092147-58812018-12-0124713551359218Micro-Sized glucose biosensor based on composite pH sensorÖzlem TavukçuoğluDerya Bal AltuntaşToday's scientific and technical advances have led to significant advances in biosensor technology, leading to widespread use of biosensors in areas such as food technology, the environment, pharmaceuticals and clinical diagnostics, biochemistry, and analytical chemistry. Improvements in the ion-selective sensor technology used in the preparation of potentiometric biosensors and the increase in the number of sensor materials have also accelerated the development of new types of potentiometric biosensors. Thus, in this study, information is given on the development of a new micro sized potentiometric glucose biosensor based on composite pH sensor. Glucose oxidase was immobilized on the composite layer as the biorecognition element. The surface of glucose biosensor based composite pH sensing matrices was first examined for electrochemical elucidation by using cyclic voltammetry and electrochemical impedance spectroscopy. The rate of electron transfer resulted in a stable response behavior of the biosensor and made it a suitable potentiometric sensor for detection of glucose. A linear response in concentration range from 5x10-5 to 1x10-1 mol/L was obtained with a detection limit of 2x10-5 mol/L for the potentiometric detection of glucose. The biosensor exhibited a fast response time (10 s), had good stability, and an extended lifetime.https://dergipark.org.tr/tr/pub/pajes/issue/41410/504353solid-state composite sensorminiatruizationdiabet follow-upglucose biosensorkatı-hal kompozit ph sensörminyatürizasyondiyabet takibiglikoz biyosensör
spellingShingle Özlem Tavukçuoğlu
Derya Bal Altuntaş
Micro-Sized glucose biosensor based on composite pH sensor
Pamukkale University Journal of Engineering Sciences
solid-state composite sensor
miniatruization
diabet follow-up
glucose biosensor
katı-hal kompozit ph sensör
minyatürizasyon
diyabet takibi
glikoz biyosensör
title Micro-Sized glucose biosensor based on composite pH sensor
title_full Micro-Sized glucose biosensor based on composite pH sensor
title_fullStr Micro-Sized glucose biosensor based on composite pH sensor
title_full_unstemmed Micro-Sized glucose biosensor based on composite pH sensor
title_short Micro-Sized glucose biosensor based on composite pH sensor
title_sort micro sized glucose biosensor based on composite ph sensor
topic solid-state composite sensor
miniatruization
diabet follow-up
glucose biosensor
katı-hal kompozit ph sensör
minyatürizasyon
diyabet takibi
glikoz biyosensör
url https://dergipark.org.tr/tr/pub/pajes/issue/41410/504353
work_keys_str_mv AT ozlemtavukcuoglu microsizedglucosebiosensorbasedoncompositephsensor
AT deryabalaltuntas microsizedglucosebiosensorbasedoncompositephsensor