Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication
Abstract Background The treatment of Ewing sarcoma, an aggressive bone and soft tissue sarcoma, is associated with suboptimal outcomes and significant side-effects. Consequently, there is an urgent need to identify novel therapies that will improve outcomes for children and adults with Ewing sarcoma...
Main Authors: | Torin Waters, Kelli L. Goss, Stacia L. Koppenhafer, William W. Terry, David J. Gordon |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-11-01
|
Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-020-07668-6 |
Similar Items
-
Extraskeletal Ewing sarcoma of the sciatic nerve
by: Daniel Heller, MD, et al.
Published: (2023-03-01) -
Ewing`s Sarcoma
by: Agnieszka Budny, et al.
Published: (2017-06-01) -
Ewing`s Sarcoma
by: Agnieszka Budny, et al.
Published: (2017-06-01) -
Primary Ewing Sarcoma of the Thyroid—Eight Cases in a Decade: A Case Report and Literature Review
by: Paweł Kabata, et al.
Published: (2017-10-01) -
Primary retroperitoneal Ewing's sarcoma in a young woman
by: Li Kong, et al.
Published: (2024-02-01)