Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in Thailand
Abstract Background Interactions between humans and animals are the key elements of zoonotic spillover leading to zoonotic disease emergence. Research to understand the high-risk behaviors associated with disease transmission at the human-animal interface is limited, and few consider regional and lo...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-022-07439-7 |
| _version_ | 1828322256374202368 |
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| author | Su Yadana Thaniwan Cheun-Arom Hongying Li Emily Hagan Emma Mendelsohn Alice Latinne Stephanie Martinez Opass Putcharoen Janthira Homvijitkul Onarnong Sathaporntheera Nit Rattanapreeda Pongtorn Chartpituck Supalak Yamsakul Krairoek Sutham Supharoek Komolsiri Sonjai Pornphatthananikhom Sininat Petcharat Weenassarin Ampoot Leilani Francisco Thiravat Hemachudha Peter Daszak Kevin J. Olival Supaporn Wacharapluesadee |
| author_facet | Su Yadana Thaniwan Cheun-Arom Hongying Li Emily Hagan Emma Mendelsohn Alice Latinne Stephanie Martinez Opass Putcharoen Janthira Homvijitkul Onarnong Sathaporntheera Nit Rattanapreeda Pongtorn Chartpituck Supalak Yamsakul Krairoek Sutham Supharoek Komolsiri Sonjai Pornphatthananikhom Sininat Petcharat Weenassarin Ampoot Leilani Francisco Thiravat Hemachudha Peter Daszak Kevin J. Olival Supaporn Wacharapluesadee |
| author_sort | Su Yadana |
| collection | DOAJ |
| description | Abstract Background Interactions between humans and animals are the key elements of zoonotic spillover leading to zoonotic disease emergence. Research to understand the high-risk behaviors associated with disease transmission at the human-animal interface is limited, and few consider regional and local contexts. Objective This study employed an integrated behavioral–biological surveillance approach for the early detection of novel and known zoonotic viruses in potentially high-risk populations, in an effort to identify risk factors for spillover and to determine potential foci for risk-mitigation measures. Method Participants were enrolled at two community-based sites (n = 472) in eastern and western Thailand and two hospital (clinical) sites (n = 206) in northeastern and central Thailand. A behavioral questionnaire was administered to understand participants’ demographics, living conditions, health history, and animal-contact behaviors and attitudes. Biological specimens were tested for coronaviruses, filoviruses, flaviviruses, influenza viruses, and paramyxoviruses using pan (consensus) RNA Virus assays. Results Overall 61/678 (9%) of participants tested positive for the viral families screened which included influenza viruses (75%), paramyxoviruses (15%), human coronaviruses (3%), flaviviruses (3%), and enteroviruses (3%). The most salient predictors of reporting unusual symptoms (i.e., any illness or sickness that is not known or recognized in the community or diagnosed by medical providers) in the past year were having other household members who had unusual symptoms and being scratched or bitten by animals in the same year. Many participants reported raising and handling poultry (10.3% and 24.2%), swine (2%, 14.6%), and cattle (4.9%, 7.8%) and several participants also reported eating raw or undercooked meat of these animals (2.2%, 5.5%, 10.3% respectively). Twenty four participants (3.5%) reported handling bats or having bats in the house roof. Gender, age, and livelihood activities were shown to be significantly associated with participants’ interactions with animals. Participants’ knowledge of risks influenced their health-seeking behavior. Conclusion The results suggest that there is a high level of interaction between humans, livestock, and wild animals in communities at sites we investigated in Thailand. This study highlights important differences among demographic and occupational risk factors as they relate to animal contact and zoonotic disease risk, which can be used by policymakers and local public health programs to build more effective surveillance strategies and behavior-focused interventions. |
| first_indexed | 2024-04-13T18:38:18Z |
| format | Article |
| id | doaj.art-c6dfcff7afde4dd2b8ef42f1107b46e4 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-13T18:38:18Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-c6dfcff7afde4dd2b8ef42f1107b46e42022-12-22T02:34:49ZengBMCBMC Infectious Diseases1471-23342022-05-0122111810.1186/s12879-022-07439-7Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in ThailandSu Yadana0Thaniwan Cheun-Arom1Hongying Li2Emily Hagan3Emma Mendelsohn4Alice Latinne5Stephanie Martinez6Opass Putcharoen7Janthira Homvijitkul8Onarnong Sathaporntheera9Nit Rattanapreeda10Pongtorn Chartpituck11Supalak Yamsakul12Krairoek Sutham13Supharoek Komolsiri14Sonjai Pornphatthananikhom15Sininat Petcharat16Weenassarin Ampoot17Leilani Francisco18Thiravat Hemachudha19Peter Daszak20Kevin J. Olival21Supaporn Wacharapluesadee22EcoHealth AllianceDepartment of Biology, Faculty of Science, Ramkhamhaeng UniversityEcoHealth AllianceEcoHealth AllianceEcoHealth AllianceWildlife Conservation Society, Viet Nam Country ProgramEcoHealth AllianceDivision of Infectious Diseases, Faculty of Medicine, Thai Red Cross Emerging Infectious Diseases Clinical Centre, King Chulalongkorn Memorial Hospital, Chulalongkorn UniversityLoei HospitalLoei HospitalLoei HospitalThe Office of Disease Prevention and Control 5The Office of Disease Prevention and Control 5The Office of Disease Prevention and Control 5The Office of Disease Prevention and Control 5Wat-Luang Health Promoting HospitalThai Red Cross Emerging Infectious Diseases-Health Science Centre, Faculty of Medicine, World Health Organization Collaborating Centre for Research and Training On Viral Zoonoses, Chulalongkorn Hospital, Chulalongkorn UniversityThai Red Cross Emerging Infectious Diseases-Health Science Centre, Faculty of Medicine, World Health Organization Collaborating Centre for Research and Training On Viral Zoonoses, Chulalongkorn Hospital, Chulalongkorn UniversityThe Henry M. Jackson Foundation for the Advancement of Military MedicineThai Red Cross Emerging Infectious Diseases-Health Science Centre, Faculty of Medicine, World Health Organization Collaborating Centre for Research and Training On Viral Zoonoses, Chulalongkorn Hospital, Chulalongkorn UniversityEcoHealth AllianceEcoHealth AllianceThai Red Cross Emerging Infectious Diseases Clinical Centre, King Chulalongkorn Memorial HospitalAbstract Background Interactions between humans and animals are the key elements of zoonotic spillover leading to zoonotic disease emergence. Research to understand the high-risk behaviors associated with disease transmission at the human-animal interface is limited, and few consider regional and local contexts. Objective This study employed an integrated behavioral–biological surveillance approach for the early detection of novel and known zoonotic viruses in potentially high-risk populations, in an effort to identify risk factors for spillover and to determine potential foci for risk-mitigation measures. Method Participants were enrolled at two community-based sites (n = 472) in eastern and western Thailand and two hospital (clinical) sites (n = 206) in northeastern and central Thailand. A behavioral questionnaire was administered to understand participants’ demographics, living conditions, health history, and animal-contact behaviors and attitudes. Biological specimens were tested for coronaviruses, filoviruses, flaviviruses, influenza viruses, and paramyxoviruses using pan (consensus) RNA Virus assays. Results Overall 61/678 (9%) of participants tested positive for the viral families screened which included influenza viruses (75%), paramyxoviruses (15%), human coronaviruses (3%), flaviviruses (3%), and enteroviruses (3%). The most salient predictors of reporting unusual symptoms (i.e., any illness or sickness that is not known or recognized in the community or diagnosed by medical providers) in the past year were having other household members who had unusual symptoms and being scratched or bitten by animals in the same year. Many participants reported raising and handling poultry (10.3% and 24.2%), swine (2%, 14.6%), and cattle (4.9%, 7.8%) and several participants also reported eating raw or undercooked meat of these animals (2.2%, 5.5%, 10.3% respectively). Twenty four participants (3.5%) reported handling bats or having bats in the house roof. Gender, age, and livelihood activities were shown to be significantly associated with participants’ interactions with animals. Participants’ knowledge of risks influenced their health-seeking behavior. Conclusion The results suggest that there is a high level of interaction between humans, livestock, and wild animals in communities at sites we investigated in Thailand. This study highlights important differences among demographic and occupational risk factors as they relate to animal contact and zoonotic disease risk, which can be used by policymakers and local public health programs to build more effective surveillance strategies and behavior-focused interventions.https://doi.org/10.1186/s12879-022-07439-7SurveillanceBehavioral surveillanceZoonotic riskHuman–animal interactionRisk perceptionCoronavirus |
| spellingShingle | Su Yadana Thaniwan Cheun-Arom Hongying Li Emily Hagan Emma Mendelsohn Alice Latinne Stephanie Martinez Opass Putcharoen Janthira Homvijitkul Onarnong Sathaporntheera Nit Rattanapreeda Pongtorn Chartpituck Supalak Yamsakul Krairoek Sutham Supharoek Komolsiri Sonjai Pornphatthananikhom Sininat Petcharat Weenassarin Ampoot Leilani Francisco Thiravat Hemachudha Peter Daszak Kevin J. Olival Supaporn Wacharapluesadee Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in Thailand BMC Infectious Diseases Surveillance Behavioral surveillance Zoonotic risk Human–animal interaction Risk perception Coronavirus |
| title | Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in Thailand |
| title_full | Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in Thailand |
| title_fullStr | Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in Thailand |
| title_full_unstemmed | Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in Thailand |
| title_short | Behavioral–biological surveillance of emerging infectious diseases among a dynamic cohort in Thailand |
| title_sort | behavioral biological surveillance of emerging infectious diseases among a dynamic cohort in thailand |
| topic | Surveillance Behavioral surveillance Zoonotic risk Human–animal interaction Risk perception Coronavirus |
| url | https://doi.org/10.1186/s12879-022-07439-7 |
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