Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo Nation
(1) Background: Exfoliation syndrome (XFS) is a common cause of secondary open angle glaucoma. In 1971, Faulkner et al. estimated the prevalence of XFS among 50 Navajo Nation residents as 38%. Given that XFS can cause irreversible blindness secondary to glaucoma (XFG), this study aims to identify th...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Vision |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2411-5150/6/4/61 |
| _version_ | 1797454927932424192 |
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| author | Ayesha Patil Cole Swiston Ryan T. Wallace Chase Paulson Matthew E. Conley Lori McCoy Craig Chaya Barbara Wirostko |
| author_facet | Ayesha Patil Cole Swiston Ryan T. Wallace Chase Paulson Matthew E. Conley Lori McCoy Craig Chaya Barbara Wirostko |
| author_sort | Ayesha Patil |
| collection | DOAJ |
| description | (1) Background: Exfoliation syndrome (XFS) is a common cause of secondary open angle glaucoma. In 1971, Faulkner et al. estimated the prevalence of XFS among 50 Navajo Nation residents as 38%. Given that XFS can cause irreversible blindness secondary to glaucoma (XFG), this study aims to identify the current prevalence of XFS among Navajo Nation residents within the Four Corners region of the U.S. (2) Methods: A retrospective chart review was conducted from 2016 to 2021 for patients aged 18 and older. All patients with XFS or XFG diagnosed by slit lamp exam were identified through chart review. (3) Results: Of the 1152 patient charts available for review, eight patients (11 eyes) were diagnosed with XFS with three patients (4 eyes) demonstrating concomitant XFG. Within this XFS population, 50% of the patients identified as male, with a mean age of 73 years. The overall prevalence of XFS was 0.7% and the overall prevalence of XFG was found to be 0.26%. The rate of XFG among patients with XFS was 37.5%. (4) Conclusion: Compared to Faulkner’s study of Navajo Nation residents in 1971, our findings show a considerably lower prevalence of XFS at 0.7%. We present the largest study to date of XFS among this population. |
| first_indexed | 2024-03-09T15:45:08Z |
| format | Article |
| id | doaj.art-c6e3e5747c1943c9bc81cc46c00a3d1b |
| institution | Directory Open Access Journal |
| issn | 2411-5150 |
| language | English |
| last_indexed | 2024-03-09T15:45:08Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vision |
| spelling | doaj.art-c6e3e5747c1943c9bc81cc46c00a3d1b2023-11-24T18:40:30ZengMDPI AGVision2411-51502022-10-01646110.3390/vision6040061Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo NationAyesha Patil0Cole Swiston1Ryan T. Wallace2Chase Paulson3Matthew E. Conley4Lori McCoy5Craig Chaya6Barbara Wirostko7Department of Ophthalmology/Visual Sciences, John A Moran Eye Center, University of Utah Health, Salt Lake City, UT 84132, USADepartment of Ophthalmology/Visual Sciences, John A Moran Eye Center, University of Utah Health, Salt Lake City, UT 84132, USADepartment of Ophthalmology/Visual Sciences, John A Moran Eye Center, University of Utah Health, Salt Lake City, UT 84132, USASchool of Medicine, University of Utah, Salt Lake City, UT 84132, USASchool of Medicine, University of Utah, Salt Lake City, UT 84132, USADepartment of Ophthalmology/Visual Sciences, John A Moran Eye Center, University of Utah Health, Salt Lake City, UT 84132, USADepartment of Ophthalmology/Visual Sciences, John A Moran Eye Center, University of Utah Health, Salt Lake City, UT 84132, USADepartment of Ophthalmology/Visual Sciences, John A Moran Eye Center, University of Utah Health, Salt Lake City, UT 84132, USA(1) Background: Exfoliation syndrome (XFS) is a common cause of secondary open angle glaucoma. In 1971, Faulkner et al. estimated the prevalence of XFS among 50 Navajo Nation residents as 38%. Given that XFS can cause irreversible blindness secondary to glaucoma (XFG), this study aims to identify the current prevalence of XFS among Navajo Nation residents within the Four Corners region of the U.S. (2) Methods: A retrospective chart review was conducted from 2016 to 2021 for patients aged 18 and older. All patients with XFS or XFG diagnosed by slit lamp exam were identified through chart review. (3) Results: Of the 1152 patient charts available for review, eight patients (11 eyes) were diagnosed with XFS with three patients (4 eyes) demonstrating concomitant XFG. Within this XFS population, 50% of the patients identified as male, with a mean age of 73 years. The overall prevalence of XFS was 0.7% and the overall prevalence of XFG was found to be 0.26%. The rate of XFG among patients with XFS was 37.5%. (4) Conclusion: Compared to Faulkner’s study of Navajo Nation residents in 1971, our findings show a considerably lower prevalence of XFS at 0.7%. We present the largest study to date of XFS among this population.https://www.mdpi.com/2411-5150/6/4/61exfoliation syndromeexfoliation glaucomahealth disparitiesepidemiologyglaucomapseudoexfoliation syndrome |
| spellingShingle | Ayesha Patil Cole Swiston Ryan T. Wallace Chase Paulson Matthew E. Conley Lori McCoy Craig Chaya Barbara Wirostko Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo Nation Vision exfoliation syndrome exfoliation glaucoma health disparities epidemiology glaucoma pseudoexfoliation syndrome |
| title | Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo Nation |
| title_full | Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo Nation |
| title_fullStr | Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo Nation |
| title_full_unstemmed | Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo Nation |
| title_short | Exfoliation Syndrome and Exfoliation Glaucoma in the Navajo Nation |
| title_sort | exfoliation syndrome and exfoliation glaucoma in the navajo nation |
| topic | exfoliation syndrome exfoliation glaucoma health disparities epidemiology glaucoma pseudoexfoliation syndrome |
| url | https://www.mdpi.com/2411-5150/6/4/61 |
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