Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic

Patients with moderate to severe dry eyes are often screened at the Dry Eye Clinic to rule out connective tissue diseases. Rheumatoid factor (RF) is one of the screening tools to rule out rheumatoid arthritis (RA). Patients who turn out positive for the RF are often subjected to anti-CCP antibody ev...

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Main Authors: Prabhakar Singh, Arvind Kumar, Prakash Chandra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=1;spage=236;epage=238;aulast=Singh
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author Prabhakar Singh
Arvind Kumar
Prakash Chandra
author_facet Prabhakar Singh
Arvind Kumar
Prakash Chandra
author_sort Prabhakar Singh
collection DOAJ
description Patients with moderate to severe dry eyes are often screened at the Dry Eye Clinic to rule out connective tissue diseases. Rheumatoid factor (RF) is one of the screening tools to rule out rheumatoid arthritis (RA). Patients who turn out positive for the RF are often subjected to anti-CCP antibody evaluation for confirmation of disease. This article tries to highlight 3 cases of negative and anti-CCP antibody positive cases which presented to the ophthalmic clinic, unaware of their systemic status. Though RF is the cheapest modality to screen for RA, it is not always a reliable marker. One should order anti-CCP antibody for patients where suspicion is high, despite RF being normal.
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spelling doaj.art-c6e6c3f16aa04efb8d1b9e331d7ce7dd2022-12-21T18:15:36ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-0168123623810.4103/ijo.IJO_526_19Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinicPrabhakar SinghArvind KumarPrakash ChandraPatients with moderate to severe dry eyes are often screened at the Dry Eye Clinic to rule out connective tissue diseases. Rheumatoid factor (RF) is one of the screening tools to rule out rheumatoid arthritis (RA). Patients who turn out positive for the RF are often subjected to anti-CCP antibody evaluation for confirmation of disease. This article tries to highlight 3 cases of negative and anti-CCP antibody positive cases which presented to the ophthalmic clinic, unaware of their systemic status. Though RF is the cheapest modality to screen for RA, it is not always a reliable marker. One should order anti-CCP antibody for patients where suspicion is high, despite RF being normal.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=1;spage=236;epage=238;aulast=Singhanti-ccp antibodyophthalmic clinicrheumatoid factor
spellingShingle Prabhakar Singh
Arvind Kumar
Prakash Chandra
Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic
Indian Journal of Ophthalmology
anti-ccp antibody
ophthalmic clinic
rheumatoid factor
title Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic
title_full Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic
title_fullStr Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic
title_full_unstemmed Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic
title_short Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic
title_sort rheumatoid factor versus anti cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic
topic anti-ccp antibody
ophthalmic clinic
rheumatoid factor
url http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=1;spage=236;epage=238;aulast=Singh
work_keys_str_mv AT prabhakarsingh rheumatoidfactorversusanticycliccitrullinatedpeptideantibodyasscreeningtoolforrheumatoidarthritisinanophthalmicclinic
AT arvindkumar rheumatoidfactorversusanticycliccitrullinatedpeptideantibodyasscreeningtoolforrheumatoidarthritisinanophthalmicclinic
AT prakashchandra rheumatoidfactorversusanticycliccitrullinatedpeptideantibodyasscreeningtoolforrheumatoidarthritisinanophthalmicclinic