Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis
Drugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patie...
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Format: | Article |
Language: | English |
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Karger Publishers
2010-09-01
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Series: | Case Reports in Gastroenterology |
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Online Access: | http://www.karger.com/Article/FullText/320591 |
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author | Jean Louis Frossard Christian Felley Pierre Michetti |
author_facet | Jean Louis Frossard Christian Felley Pierre Michetti |
author_sort | Jean Louis Frossard |
collection | DOAJ |
description | Drugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patient with intestinal inflammatory bowel disease that needed to be treated with subsequent antiinflammatory agents. Genetic mutation in the CFTR gene was found in the patient that led us to postulate that CFTR was a trigger for drug-induced acute pancreatitis. In conclusion, genetic analysis should be advised in case of recurrent pancreatitis in patient with intestinal inflammatory bowel disease. |
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format | Article |
id | doaj.art-c6e818270543404ba862732f4604caa1 |
institution | Directory Open Access Journal |
issn | 1662-0631 |
language | English |
last_indexed | 2024-12-22T13:00:40Z |
publishDate | 2010-09-01 |
publisher | Karger Publishers |
record_format | Article |
series | Case Reports in Gastroenterology |
spelling | doaj.art-c6e818270543404ba862732f4604caa12022-12-21T18:25:01ZengKarger PublishersCase Reports in Gastroenterology1662-06312010-09-014330430610.1159/000320591320591Recurrent Acute Pancreatitis and Therapy for Ulcerative ColitisJean Louis FrossardChristian FelleyPierre MichettiDrugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patient with intestinal inflammatory bowel disease that needed to be treated with subsequent antiinflammatory agents. Genetic mutation in the CFTR gene was found in the patient that led us to postulate that CFTR was a trigger for drug-induced acute pancreatitis. In conclusion, genetic analysis should be advised in case of recurrent pancreatitis in patient with intestinal inflammatory bowel disease.http://www.karger.com/Article/FullText/320591Acute pancreatitisCystic fibrosis conductance regulatorInflammatory bowel disease |
spellingShingle | Jean Louis Frossard Christian Felley Pierre Michetti Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis Case Reports in Gastroenterology Acute pancreatitis Cystic fibrosis conductance regulator Inflammatory bowel disease |
title | Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis |
title_full | Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis |
title_fullStr | Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis |
title_full_unstemmed | Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis |
title_short | Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis |
title_sort | recurrent acute pancreatitis and therapy for ulcerative colitis |
topic | Acute pancreatitis Cystic fibrosis conductance regulator Inflammatory bowel disease |
url | http://www.karger.com/Article/FullText/320591 |
work_keys_str_mv | AT jeanlouisfrossard recurrentacutepancreatitisandtherapyforulcerativecolitis AT christianfelley recurrentacutepancreatitisandtherapyforulcerativecolitis AT pierremichetti recurrentacutepancreatitisandtherapyforulcerativecolitis |