Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis

Drugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patie...

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Main Authors: Jean Louis Frossard, Christian Felley, Pierre Michetti
Format: Article
Language:English
Published: Karger Publishers 2010-09-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://www.karger.com/Article/FullText/320591
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author Jean Louis Frossard
Christian Felley
Pierre Michetti
author_facet Jean Louis Frossard
Christian Felley
Pierre Michetti
author_sort Jean Louis Frossard
collection DOAJ
description Drugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patient with intestinal inflammatory bowel disease that needed to be treated with subsequent antiinflammatory agents. Genetic mutation in the CFTR gene was found in the patient that led us to postulate that CFTR was a trigger for drug-induced acute pancreatitis. In conclusion, genetic analysis should be advised in case of recurrent pancreatitis in patient with intestinal inflammatory bowel disease.
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spelling doaj.art-c6e818270543404ba862732f4604caa12022-12-21T18:25:01ZengKarger PublishersCase Reports in Gastroenterology1662-06312010-09-014330430610.1159/000320591320591Recurrent Acute Pancreatitis and Therapy for Ulcerative ColitisJean Louis FrossardChristian FelleyPierre MichettiDrugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patient with intestinal inflammatory bowel disease that needed to be treated with subsequent antiinflammatory agents. Genetic mutation in the CFTR gene was found in the patient that led us to postulate that CFTR was a trigger for drug-induced acute pancreatitis. In conclusion, genetic analysis should be advised in case of recurrent pancreatitis in patient with intestinal inflammatory bowel disease.http://www.karger.com/Article/FullText/320591Acute pancreatitisCystic fibrosis conductance regulatorInflammatory bowel disease
spellingShingle Jean Louis Frossard
Christian Felley
Pierre Michetti
Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis
Case Reports in Gastroenterology
Acute pancreatitis
Cystic fibrosis conductance regulator
Inflammatory bowel disease
title Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis
title_full Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis
title_fullStr Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis
title_full_unstemmed Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis
title_short Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis
title_sort recurrent acute pancreatitis and therapy for ulcerative colitis
topic Acute pancreatitis
Cystic fibrosis conductance regulator
Inflammatory bowel disease
url http://www.karger.com/Article/FullText/320591
work_keys_str_mv AT jeanlouisfrossard recurrentacutepancreatitisandtherapyforulcerativecolitis
AT christianfelley recurrentacutepancreatitisandtherapyforulcerativecolitis
AT pierremichetti recurrentacutepancreatitisandtherapyforulcerativecolitis