Soluble Collectin 11 (CL-11) Acts as an Immunosuppressive Molecule Potentially Used by Stem Cell-Derived Retinal Epithelial Cells to Modulate T Cell Response

Soluble Collectin 11 (CL-11) Acts as an Immunosuppressive Molecule Potentially Used by Stem Cell-Derived Retinal Epithelial Cells to Modulate T Cell Response

Retinal pigment epithelium (RPE) cell allotransplantation is seen as a possible solution to retinal diseases. However, the RPE-complement system triggered by the binding of collectin-11 (CL-11) is a potential barrier for RPE transplantation as the complement-mediated inflammatory response may promot...

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Bibliographic Details
Main Authors:	Giorgia Fanelli, Marco Romano, Giovanna Lombardi, Steven H. Sacks
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Series:	Cells
Subjects:	T cell activation stem cell-derived retinal pigment epithelium cells Collectin 11 transplantation
Online Access:	https://www.mdpi.com/2073-4409/12/13/1805

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