Review of in-vivo characterisation of corneal biomechanics

The study of corneal biomechanics in vivo has been evolving fast in recent years. While an organised corneal structure is necessary for its transparency, resistance to occasional external insults and bearing the intraocular pressure (IOP), which several clinically relevant events can disturb. This r...

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Main Authors: Bernardo T. Lopes, FangJun Bao, JunJie Wang, XiaoYu Liu, LiZhen Wang, Ahmed Abass, Ashkan Eliasy, Ahmed Elsheikh
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Medicine in Novel Technology and Devices
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590093521000175
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author Bernardo T. Lopes
FangJun Bao
JunJie Wang
XiaoYu Liu
LiZhen Wang
Ahmed Abass
Ashkan Eliasy
Ahmed Elsheikh
author_facet Bernardo T. Lopes
FangJun Bao
JunJie Wang
XiaoYu Liu
LiZhen Wang
Ahmed Abass
Ashkan Eliasy
Ahmed Elsheikh
author_sort Bernardo T. Lopes
collection DOAJ
description The study of corneal biomechanics in vivo has been evolving fast in recent years. While an organised corneal structure is necessary for its transparency, resistance to occasional external insults and bearing the intraocular pressure (IOP), which several clinically relevant events can disturb. This review focuses on three techniques that are available for clinical use, namely the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, NY, USA), the Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) and the Brillouin Optical Scattering System (Intelon Optics Inc., Lexington, MA, USA). The principles and the main parameters of each device are discussed along with their strategies to improve accuracy in the IOP measurement, corneal ectasia diagnosis, evaluation of corneal cross-linking procedures, and planning of corneal refractive surgeries.
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spelling doaj.art-c6e9a099d05144f5b5336fd6e4aebad72022-12-21T18:35:48ZengElsevierMedicine in Novel Technology and Devices2590-09352021-09-0111100073Review of in-vivo characterisation of corneal biomechanicsBernardo T. Lopes0FangJun Bao1JunJie Wang2XiaoYu Liu3LiZhen Wang4Ahmed Abass5Ashkan Eliasy6Ahmed Elsheikh7School of Engineering, University of Liverpool, Liverpool, UK; Department of Ophthalmology, Federal Univerisity of Sao Paulo (UNIFESP), Sao Paulo, Brazil; Corresponding author. School of Engineering, University of Liverpool, Liverpool, L69 3GH, UK.Eye Hospital, Wenzhou Medical University, Wenzhou, China; The Institution of Ocular Biomechanics, Wenzhou Medical University, Wenzhou, China; Corresponding author. Eye Hospital, Wenzhou Medical University, WenZhou City, ZheJiang Prov, 325027, China.Eye Hospital, Wenzhou Medical University, Wenzhou, China; The Institution of Ocular Biomechanics, Wenzhou Medical University, Wenzhou, ChinaKey Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China; Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, ChinaKey Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China; Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, ChinaSchool of Engineering, University of Liverpool, Liverpool, UKSchool of Engineering, University of Liverpool, Liverpool, UKSchool of Engineering, University of Liverpool, Liverpool, UK; Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, China; National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UKThe study of corneal biomechanics in vivo has been evolving fast in recent years. While an organised corneal structure is necessary for its transparency, resistance to occasional external insults and bearing the intraocular pressure (IOP), which several clinically relevant events can disturb. This review focuses on three techniques that are available for clinical use, namely the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, NY, USA), the Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) and the Brillouin Optical Scattering System (Intelon Optics Inc., Lexington, MA, USA). The principles and the main parameters of each device are discussed along with their strategies to improve accuracy in the IOP measurement, corneal ectasia diagnosis, evaluation of corneal cross-linking procedures, and planning of corneal refractive surgeries.http://www.sciencedirect.com/science/article/pii/S2590093521000175Corneal biomechanicsCorneal diagnosisIntraocular pressureCorneal ectasiaCorneal cross linking
spellingShingle Bernardo T. Lopes
FangJun Bao
JunJie Wang
XiaoYu Liu
LiZhen Wang
Ahmed Abass
Ashkan Eliasy
Ahmed Elsheikh
Review of in-vivo characterisation of corneal biomechanics
Medicine in Novel Technology and Devices
Corneal biomechanics
Corneal diagnosis
Intraocular pressure
Corneal ectasia
Corneal cross linking
title Review of in-vivo characterisation of corneal biomechanics
title_full Review of in-vivo characterisation of corneal biomechanics
title_fullStr Review of in-vivo characterisation of corneal biomechanics
title_full_unstemmed Review of in-vivo characterisation of corneal biomechanics
title_short Review of in-vivo characterisation of corneal biomechanics
title_sort review of in vivo characterisation of corneal biomechanics
topic Corneal biomechanics
Corneal diagnosis
Intraocular pressure
Corneal ectasia
Corneal cross linking
url http://www.sciencedirect.com/science/article/pii/S2590093521000175
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