Oxysterol binding protein-like 3 (OSBPL3) is a novel driver gene that promotes tumor growth in part through R-Ras/Akt signaling in gastric cancer

Abstract Gastric cancer (GC) is one of the most lethal malignant tumors. To improve the prognosis of GC, the identification of novel driver genes as therapeutic targets is in urgent need. Here, we aimed to identify novel driver genes and clarify their roles in gastric cancer. OSBPL3 was identified a...

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Bibliographic Details
Main Authors: Qingjiang Hu, Takaaki Masuda, Kensuke Koike, Kuniaki Sato, Taro Tobo, Shotaro Kuramitsu, Akihiro Kitagawa, Atsushi Fujii, Miwa Noda, Yusuke Tsuruda, Hajime Otsu, Yosuke Kuroda, Shuhei Ito, Eiji Oki, Koshi Mimori
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98485-9