Integrated Analysis of the Alterations in Gut Microbiota and Metabolites of Mice Induced After Long-Term Intervention With Different Antibiotics

Integrated Analysis of the Alterations in Gut Microbiota and Metabolites of Mice Induced After Long-Term Intervention With Different Antibiotics

ObjectivesWe aimed to study the effect of antibiotic-induced disruption of gut microbiome on host metabolomes and inflammatory responses after long-term use of antibiotics.MethodsA total of three groups of 3-week-old female C57BL/6 mice (n = 44) were continuously treated with vancomycin (VAN), polym...

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Bibliographic Details
Main Authors: Nan Zhang, Jun Liu, Zhiyun Chen, Ning Chen, Fangyan Gu, Qiushui He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
microbial metabolomics
gut microbiota
inflammatory response
antibiotics
vancomycin
polymyxin B
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.832915/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.832915/full

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