Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the present
Bone sarcomas account for 7% of malignant tumors in children, and osteosarcomas make up 35–50% of them. Many patients are diagnosed at spread stages of the disease, which dictates the need to search for new approaches to treatment. At the same time, the optimal therapeutic strategy is unknown, the r...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Ltd. “The National Academy of Pediatric Science and Innovation”
2019-05-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/855 |
| _version_ | 1797875198817468416 |
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| author | M. Yu. Rykov E. R. Senzhapova |
| author_facet | M. Yu. Rykov E. R. Senzhapova |
| author_sort | M. Yu. Rykov |
| collection | DOAJ |
| description | Bone sarcomas account for 7% of malignant tumors in children, and osteosarcomas make up 35–50% of them. Many patients are diagnosed at spread stages of the disease, which dictates the need to search for new approaches to treatment. At the same time, the optimal therapeutic strategy is unknown, the results of treatment of such children remain unsatisfactory. Part I of this article describes currently used treatment regimens. Part II presents achievements in the field of personalized therapy. Thus, changes in treatment approaches illustrate the vector of development of the treatment principles of such complex diseases, being fatal for most patients a few years ago. |
| first_indexed | 2024-04-10T01:43:48Z |
| format | Article |
| id | doaj.art-c6ed7fe592444267b8d06d4c1cd41fee |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:43:48Z |
| publishDate | 2019-05-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-c6ed7fe592444267b8d06d4c1cd41fee2023-03-13T09:12:46ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282019-05-01642475110.21508/1027-4065-2019-64-2-47-51716Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the presentM. Yu. Rykov0E. R. Senzhapova1ФБГУ «Национальный медицинский исследовательский центр онкологии им. академика Н.Н. Блохина» Минздрава России; ФГАОУ ВО «Первый московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)ФБГУ «Национальный медицинский исследовательский центр онкологии им. академика Н.Н. Блохина» Минздрава РоссииBone sarcomas account for 7% of malignant tumors in children, and osteosarcomas make up 35–50% of them. Many patients are diagnosed at spread stages of the disease, which dictates the need to search for new approaches to treatment. At the same time, the optimal therapeutic strategy is unknown, the results of treatment of such children remain unsatisfactory. Part I of this article describes currently used treatment regimens. Part II presents achievements in the field of personalized therapy. Thus, changes in treatment approaches illustrate the vector of development of the treatment principles of such complex diseases, being fatal for most patients a few years ago.https://www.ped-perinatology.ru/jour/article/view/855детская онкологияостеосаркомаперсонализированная терапияхимиотерапия |
| spellingShingle | M. Yu. Rykov E. R. Senzhapova Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the present Rossijskij Vestnik Perinatologii i Pediatrii детская онкология остеосаркома персонализированная терапия химиотерапия |
| title | Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the present |
| title_full | Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the present |
| title_fullStr | Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the present |
| title_full_unstemmed | Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the present |
| title_short | Osteosarcoma – on the way to personalized therapy. Part I: standard chemotherapy in the present |
| title_sort | osteosarcoma on the way to personalized therapy part i standard chemotherapy in the present |
| topic | детская онкология остеосаркома персонализированная терапия химиотерапия |
| url | https://www.ped-perinatology.ru/jour/article/view/855 |
| work_keys_str_mv | AT myurykov osteosarcomaonthewaytopersonalizedtherapypartistandardchemotherapyinthepresent AT ersenzhapova osteosarcomaonthewaytopersonalizedtherapypartistandardchemotherapyinthepresent |