The role of apoptosis in pathogenesis of type 1 diabetes mellitus
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes i...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2010-03-01
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| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/6016 |
| _version_ | 1826588193762312192 |
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| author | Elena Vladimirovna Pekareva Tatiana Vasil'evna Nikonova Olga Mikhailovna Smirnova |
| author_facet | Elena Vladimirovna Pekareva Tatiana Vasil'evna Nikonova Olga Mikhailovna Smirnova |
| author_sort | Elena Vladimirovna Pekareva |
| collection | DOAJ |
| description | Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1. |
| first_indexed | 2024-03-08T15:22:42Z |
| format | Article |
| id | doaj.art-c6ee29cf448846dab828aa2a84d58b98 |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2025-03-14T16:37:27Z |
| publishDate | 2010-03-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-c6ee29cf448846dab828aa2a84d58b982025-02-21T09:29:27ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782010-03-01131454910.14341/2072-0351-60165974The role of apoptosis in pathogenesis of type 1 diabetes mellitusElena Vladimirovna Pekareva0Tatiana Vasil'evna Nikonova1Olga Mikhailovna Smirnova2Endocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowType 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1.https://www.dia-endojournals.ru/jour/article/view/6016fasfaslapoptosistype 1 diabetes mellitusfasfasl |
| spellingShingle | Elena Vladimirovna Pekareva Tatiana Vasil'evna Nikonova Olga Mikhailovna Smirnova The role of apoptosis in pathogenesis of type 1 diabetes mellitus Сахарный диабет fas fasl apoptosis type 1 diabetes mellitus fas fasl |
| title | The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
| title_full | The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
| title_fullStr | The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
| title_full_unstemmed | The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
| title_short | The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
| title_sort | role of apoptosis in pathogenesis of type 1 diabetes mellitus |
| topic | fas fasl apoptosis type 1 diabetes mellitus fas fasl |
| url | https://www.dia-endojournals.ru/jour/article/view/6016 |
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