The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry

Species of the genus <i>Miconia</i> are used in traditional medicine for the treatment of diseases, such as pain, throat infections, fever, and cold, and they used as depuratives, diuretics, and sedatives. This work reviewed studies carried out with <i>Miconia</i> species, hi...

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Main Authors: Viviane Bezerra da Silva, José Weverton Almeida-Bezerra, Adrielle Rodrigues Costa, Maria Flaviana Bezerra Morais-Braga, Maraiza Gregorio de Oliveira, Anderson Angel Vieira Pinheiro, Raimundo Samuel Leite Sampaio, José Walber Gonçalves Castro, Marcos Aurélio Figueiredo dos Santos, Valdilia Ribeiro de Alencar Ulisses, Maria Edilania da Silva Serafim Pereira, Dieferson Leandro de Souza, Bruno Melo de Alcântara, Maria Elizete Machado Generino, José Thyálisson da Costa Silva, Ademar Maia Filho, Sabrina Bezerra da Silva, Myunghan Moon, Bonglee Kim, José Galberto Martins da Costa
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/27/13/4132
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Summary:Species of the genus <i>Miconia</i> are used in traditional medicine for the treatment of diseases, such as pain, throat infections, fever, and cold, and they used as depuratives, diuretics, and sedatives. This work reviewed studies carried out with <i>Miconia</i> species, highlighting its ethnomedicinal uses and pharmacological and phytochemical potential. This information was collected in the main platforms of scientific research (PubMed, Scopus, and Web of Science). Our findings show that some of the traditional uses of <i>Miconia</i> are corroborated by biological and/or pharmacological assays, which demonstrated, among other properties, anti-inflammatory, analgesic, antimutagenic, antiparasitic, antioxidant, cytotoxic, and antimicrobial activities. A total of 148 chemical compounds were identified in <i>Miconia</i> species, with phenolic compounds being the main constituents found in the species of this genus. Such phytochemical investigations have demonstrated the potential of species belonging to this genus as a source of bioactive substances, thus reinforcing their medicinal and pharmacological importance.
ISSN:1420-3049