The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry

Species of the genus <i>Miconia</i> are used in traditional medicine for the treatment of diseases, such as pain, throat infections, fever, and cold, and they used as depuratives, diuretics, and sedatives. This work reviewed studies carried out with <i>Miconia</i> species, hi...

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Main Authors: Viviane Bezerra da Silva, José Weverton Almeida-Bezerra, Adrielle Rodrigues Costa, Maria Flaviana Bezerra Morais-Braga, Maraiza Gregorio de Oliveira, Anderson Angel Vieira Pinheiro, Raimundo Samuel Leite Sampaio, José Walber Gonçalves Castro, Marcos Aurélio Figueiredo dos Santos, Valdilia Ribeiro de Alencar Ulisses, Maria Edilania da Silva Serafim Pereira, Dieferson Leandro de Souza, Bruno Melo de Alcântara, Maria Elizete Machado Generino, José Thyálisson da Costa Silva, Ademar Maia Filho, Sabrina Bezerra da Silva, Myunghan Moon, Bonglee Kim, José Galberto Martins da Costa
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/13/4132
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author Viviane Bezerra da Silva
José Weverton Almeida-Bezerra
Adrielle Rodrigues Costa
Maria Flaviana Bezerra Morais-Braga
Maraiza Gregorio de Oliveira
Anderson Angel Vieira Pinheiro
Raimundo Samuel Leite Sampaio
José Walber Gonçalves Castro
Marcos Aurélio Figueiredo dos Santos
Valdilia Ribeiro de Alencar Ulisses
Maria Edilania da Silva Serafim Pereira
Dieferson Leandro de Souza
Bruno Melo de Alcântara
Maria Elizete Machado Generino
José Thyálisson da Costa Silva
Ademar Maia Filho
Sabrina Bezerra da Silva
Myunghan Moon
Bonglee Kim
José Galberto Martins da Costa
author_facet Viviane Bezerra da Silva
José Weverton Almeida-Bezerra
Adrielle Rodrigues Costa
Maria Flaviana Bezerra Morais-Braga
Maraiza Gregorio de Oliveira
Anderson Angel Vieira Pinheiro
Raimundo Samuel Leite Sampaio
José Walber Gonçalves Castro
Marcos Aurélio Figueiredo dos Santos
Valdilia Ribeiro de Alencar Ulisses
Maria Edilania da Silva Serafim Pereira
Dieferson Leandro de Souza
Bruno Melo de Alcântara
Maria Elizete Machado Generino
José Thyálisson da Costa Silva
Ademar Maia Filho
Sabrina Bezerra da Silva
Myunghan Moon
Bonglee Kim
José Galberto Martins da Costa
author_sort Viviane Bezerra da Silva
collection DOAJ
description Species of the genus <i>Miconia</i> are used in traditional medicine for the treatment of diseases, such as pain, throat infections, fever, and cold, and they used as depuratives, diuretics, and sedatives. This work reviewed studies carried out with <i>Miconia</i> species, highlighting its ethnomedicinal uses and pharmacological and phytochemical potential. This information was collected in the main platforms of scientific research (PubMed, Scopus, and Web of Science). Our findings show that some of the traditional uses of <i>Miconia</i> are corroborated by biological and/or pharmacological assays, which demonstrated, among other properties, anti-inflammatory, analgesic, antimutagenic, antiparasitic, antioxidant, cytotoxic, and antimicrobial activities. A total of 148 chemical compounds were identified in <i>Miconia</i> species, with phenolic compounds being the main constituents found in the species of this genus. Such phytochemical investigations have demonstrated the potential of species belonging to this genus as a source of bioactive substances, thus reinforcing their medicinal and pharmacological importance.
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spelling doaj.art-c6ef7499054e42c496b3c6b3b1dffb0d2023-11-30T22:14:20ZengMDPI AGMolecules1420-30492022-06-012713413210.3390/molecules27134132The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and PhytochemistryViviane Bezerra da Silva0José Weverton Almeida-Bezerra1Adrielle Rodrigues Costa2Maria Flaviana Bezerra Morais-Braga3Maraiza Gregorio de Oliveira4Anderson Angel Vieira Pinheiro5Raimundo Samuel Leite Sampaio6José Walber Gonçalves Castro7Marcos Aurélio Figueiredo dos Santos8Valdilia Ribeiro de Alencar Ulisses9Maria Edilania da Silva Serafim Pereira10Dieferson Leandro de Souza11Bruno Melo de Alcântara12Maria Elizete Machado Generino13José Thyálisson da Costa Silva14Ademar Maia Filho15Sabrina Bezerra da Silva16Myunghan Moon17Bonglee Kim18José Galberto Martins da Costa19Department of Botany, Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Recife 50670-901, BrazilDepartment of Botany, Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Recife 50670-901, BrazilLaboratory of Applied Mycology of Cariri (LMAC), Regional University of Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilLaboratory of Applied Mycology of Cariri (LMAC), Regional University of Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Federal University of Cariri (UFCA), Av. Ten. Raimundo Rocha, 1639-Cidade Universitária, Juazeiro do Norte 63048-080, BrazilInstitute for Research in Drugs and Medicines—IpeFarM, Federal University of Paraíba, Cidade Universitária, João Pessoa 58051-970, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Biological Sciences, Universidade Regional do Cariri (URCA), Av. Cel Antônio Luis, 1161, Pimenta, Crato 63105-010, BrazilDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, KoreaDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, KoreaLaboratory of Natural Products Research, Regional University of Cariri (URCA), Crato 63122-290, BrazilSpecies of the genus <i>Miconia</i> are used in traditional medicine for the treatment of diseases, such as pain, throat infections, fever, and cold, and they used as depuratives, diuretics, and sedatives. This work reviewed studies carried out with <i>Miconia</i> species, highlighting its ethnomedicinal uses and pharmacological and phytochemical potential. This information was collected in the main platforms of scientific research (PubMed, Scopus, and Web of Science). Our findings show that some of the traditional uses of <i>Miconia</i> are corroborated by biological and/or pharmacological assays, which demonstrated, among other properties, anti-inflammatory, analgesic, antimutagenic, antiparasitic, antioxidant, cytotoxic, and antimicrobial activities. A total of 148 chemical compounds were identified in <i>Miconia</i> species, with phenolic compounds being the main constituents found in the species of this genus. Such phytochemical investigations have demonstrated the potential of species belonging to this genus as a source of bioactive substances, thus reinforcing their medicinal and pharmacological importance.https://www.mdpi.com/1420-3049/27/13/4132bioactivityethnobotanyethnopharmacologymedicinal plantsnatural product
spellingShingle Viviane Bezerra da Silva
José Weverton Almeida-Bezerra
Adrielle Rodrigues Costa
Maria Flaviana Bezerra Morais-Braga
Maraiza Gregorio de Oliveira
Anderson Angel Vieira Pinheiro
Raimundo Samuel Leite Sampaio
José Walber Gonçalves Castro
Marcos Aurélio Figueiredo dos Santos
Valdilia Ribeiro de Alencar Ulisses
Maria Edilania da Silva Serafim Pereira
Dieferson Leandro de Souza
Bruno Melo de Alcântara
Maria Elizete Machado Generino
José Thyálisson da Costa Silva
Ademar Maia Filho
Sabrina Bezerra da Silva
Myunghan Moon
Bonglee Kim
José Galberto Martins da Costa
The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry
Molecules
bioactivity
ethnobotany
ethnopharmacology
medicinal plants
natural product
title The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry
title_full The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry
title_fullStr The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry
title_full_unstemmed The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry
title_short The Genus <i>Miconia</i> Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry
title_sort genus i miconia i ruiz pav melastomataceae ethnomedicinal uses pharmacology and phytochemistry
topic bioactivity
ethnobotany
ethnopharmacology
medicinal plants
natural product
url https://www.mdpi.com/1420-3049/27/13/4132
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