African Swine Fever Virus Isolate, Georgia, 2007

African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia i...

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Main Authors: Rebecca J. Rowlands, Vincent Michaud, Livio Heath, Geoff Hutchings, Chris Oura, Wilna Vosloo, Rahana Dwarka, Tinatin Onashvili, Emmanuel Albina, Linda K. Dixon
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2008-12-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/14/12/08-0591_article
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author Rebecca J. Rowlands
Vincent Michaud
Livio Heath
Geoff Hutchings
Chris Oura
Wilna Vosloo
Rahana Dwarka
Tinatin Onashvili
Emmanuel Albina
Linda K. Dixon
author_facet Rebecca J. Rowlands
Vincent Michaud
Livio Heath
Geoff Hutchings
Chris Oura
Wilna Vosloo
Rahana Dwarka
Tinatin Onashvili
Emmanuel Albina
Linda K. Dixon
author_sort Rebecca J. Rowlands
collection DOAJ
description African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene B646L that encodes the p72 capsid protein, the complete E183L and CP204L genes, which encode the p54 and p30 proteins and the variable region of the B602L gene. Analysis of these sequences indicated that the Georgia 2007 isolate is closely related to isolates belonging to genotype II, which is circulating in Mozambique, Madagascar, and Zambia. One possibility for the spread of disease to Georgia is that pigs were fed ASFV-contaminated pork brought in on ships and, subsequently, the disease was disseminated throughout the region.
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spelling doaj.art-c6ef9af9efae4c74bd1ddf23662ed4272022-12-21T18:23:20ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592008-12-0114121870187410.3201/eid1412.080591African Swine Fever Virus Isolate, Georgia, 2007Rebecca J. RowlandsVincent MichaudLivio HeathGeoff HutchingsChris OuraWilna VoslooRahana DwarkaTinatin OnashviliEmmanuel AlbinaLinda K. DixonAfrican swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene B646L that encodes the p72 capsid protein, the complete E183L and CP204L genes, which encode the p54 and p30 proteins and the variable region of the B602L gene. Analysis of these sequences indicated that the Georgia 2007 isolate is closely related to isolates belonging to genotype II, which is circulating in Mozambique, Madagascar, and Zambia. One possibility for the spread of disease to Georgia is that pigs were fed ASFV-contaminated pork brought in on ships and, subsequently, the disease was disseminated throughout the region.https://wwwnc.cdc.gov/eid/article/14/12/08-0591_articleAfrican swine fever virusgenome analysistransmissionGeorgiaresearchRepublic of Georgia
spellingShingle Rebecca J. Rowlands
Vincent Michaud
Livio Heath
Geoff Hutchings
Chris Oura
Wilna Vosloo
Rahana Dwarka
Tinatin Onashvili
Emmanuel Albina
Linda K. Dixon
African Swine Fever Virus Isolate, Georgia, 2007
Emerging Infectious Diseases
African swine fever virus
genome analysis
transmission
Georgia
research
Republic of Georgia
title African Swine Fever Virus Isolate, Georgia, 2007
title_full African Swine Fever Virus Isolate, Georgia, 2007
title_fullStr African Swine Fever Virus Isolate, Georgia, 2007
title_full_unstemmed African Swine Fever Virus Isolate, Georgia, 2007
title_short African Swine Fever Virus Isolate, Georgia, 2007
title_sort african swine fever virus isolate georgia 2007
topic African swine fever virus
genome analysis
transmission
Georgia
research
Republic of Georgia
url https://wwwnc.cdc.gov/eid/article/14/12/08-0591_article
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