Interferon Gamma in African Trypanosome Infections: Friends or Foes?

Interferon Gamma in African Trypanosome Infections: Friends or Foes?

African trypanosomes cause fatal infections in both humans and livestock. Interferon gamma (IFN-γ) plays an essential role in resistance to African trypanosomes. However, increasing evidence suggests that IFN-γ, when excessively synthesized, also induces immunopathology, enhancing susceptibility to...

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Bibliographic Details
Main Authors:	Hui Wu, Gongguan Liu, Meiqing Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-09-01
Series:	Frontiers in Immunology
Subjects:	Trypanosoma brucei Trypanosoma congolense interferon gamma protection immunopathology
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01105/full

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