Rational Design of Toxoid Vaccine Candidates for <i>Staphylococcus aureus</i> Leukocidin AB (LukAB)

Rational Design of Toxoid Vaccine Candidates for <i>Staphylococcus aureus</i> Leukocidin AB (LukAB)

<i>Staphylococcus aureus</i> (SA) infections cause high mortality and morbidity in humans. Being central to its pathogenesis, <i>S. aureus</i> thwarts the host defense by secreting a myriad of virulence factors, including bicomponent, pore-forming leukotoxins. While all vacci...

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Bibliographic Details
Main Authors: Shweta Kailasan, Thomas Kort, Ipsita Mukherjee, Grant C. Liao, Tulasikumari Kanipakala, Nils Williston, Nader Ganjbaksh, Arundhathi Venkatasubramaniam, Frederick W. Holtsberg, Hatice Karauzum, Rajan P. Adhikari, M. Javad Aman
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
Leukocidin
<i>Staphylococcus aureus</i>
LukAB
LukGH
toxin neutralization
polyclonal antibody
toxoid vaccine
Online Access:https://www.mdpi.com/2072-6651/11/6/339

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