LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation

LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation

While dysregulation of adipocyte endocrine function plays a central role in obesity and its complications, the vast majority of adipokines remain uncharacterized. We employed bio-orthogonal non-canonical amino acid tagging (BONCAT) and mass spectrometry to comprehensively characterize the secretome...

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Bibliographic Details
Main Authors: Chan Hee J Choi, William Barr, Samir Zaman, Corey Model, Annsea Park, Mascha Koenen, Zeran Lin, Sarah K Szwed, Francois Marchildon, Audrey Crane, Thomas S Carroll, Henrik Molina, Paul Cohen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-11-01
Series:eLife
Subjects:
adipokine
secretome
LRG1
cytochrome c
obesity
insulin resistance
Online Access:https://elifesciences.org/articles/81559

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