A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy
Dapagliflozin (Farxiga), is an SGLT-2 inhibitor commonly indicated for the treatment of diabetes mellitus type 2 (DM 2), heart failure, and chronic kidney disease. One rare side effect associated with SGLT-2 inhibitors is bacterial infection of the genitalia. There are several case reports highlight...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-11-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442021002746 |
| _version_ | 1818833772286574592 |
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| author | Ethan Vargo Giovanna Leone Oren Barat Aaron Yunker Neel Parekh |
| author_facet | Ethan Vargo Giovanna Leone Oren Barat Aaron Yunker Neel Parekh |
| author_sort | Ethan Vargo |
| collection | DOAJ |
| description | Dapagliflozin (Farxiga), is an SGLT-2 inhibitor commonly indicated for the treatment of diabetes mellitus type 2 (DM 2), heart failure, and chronic kidney disease. One rare side effect associated with SGLT-2 inhibitors is bacterial infection of the genitalia. There are several case reports highlighting the incidence of Fournier's gangrene (FG) in patients who take medications within this drug class. We report a case of FG in a diabetic patient on dapagliflozin who presented following scrotal hydrocelectomy for a large-volume hydrocele. The patient was urgently taken to the operating room for scrotal debridement and recovered well in the post-operative period. |
| first_indexed | 2024-12-19T02:24:14Z |
| format | Article |
| id | doaj.art-c6f64f30f6da42308fbea8589966e431 |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-12-19T02:24:14Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-c6f64f30f6da42308fbea8589966e4312022-12-21T20:40:01ZengElsevierUrology Case Reports2214-44202021-11-0139101834A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapyEthan Vargo0Giovanna Leone1Oren Barat2Aaron Yunker3Neel Parekh4PGY-4, Cleveland Clinic Akron General Urology Program, Akron, OH, 44307, USA; Corresponding author.NEOMED, Rootstown, OH, 44272, USANEOMED, Rootstown, OH, 44272, USAPGY-5, Cleveland Clinic Akron General Urology Program, Akron, OH, 44307, USACleveland Clinic Akron General Urology Program, Akron, OH, 44307, USADapagliflozin (Farxiga), is an SGLT-2 inhibitor commonly indicated for the treatment of diabetes mellitus type 2 (DM 2), heart failure, and chronic kidney disease. One rare side effect associated with SGLT-2 inhibitors is bacterial infection of the genitalia. There are several case reports highlighting the incidence of Fournier's gangrene (FG) in patients who take medications within this drug class. We report a case of FG in a diabetic patient on dapagliflozin who presented following scrotal hydrocelectomy for a large-volume hydrocele. The patient was urgently taken to the operating room for scrotal debridement and recovered well in the post-operative period.http://www.sciencedirect.com/science/article/pii/S2214442021002746Fournier's gangreneLarge-volume hydrocelectomySGLT-2 inhibitor |
| spellingShingle | Ethan Vargo Giovanna Leone Oren Barat Aaron Yunker Neel Parekh A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy Urology Case Reports Fournier's gangrene Large-volume hydrocelectomy SGLT-2 inhibitor |
| title | A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy |
| title_full | A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy |
| title_fullStr | A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy |
| title_full_unstemmed | A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy |
| title_short | A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy |
| title_sort | case of fournier s gangrene following a large volume hydrocelectomy in a diabetic patient managed with sglt 2 inhibitor therapy |
| topic | Fournier's gangrene Large-volume hydrocelectomy SGLT-2 inhibitor |
| url | http://www.sciencedirect.com/science/article/pii/S2214442021002746 |
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