Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort study
Background: With increasing acceptance of universal developmental screening in primary care, it is essential to evaluate the local validity and psychometric properties of commonly used questionnaires like the parent-completed Ages and Stages Questionnaires, 3rd Edition (ASQ-3) in identifying develop...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Pediatrics and Neonatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957223001237 |
| _version_ | 1827367382651240448 |
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| author | Pratibha Keshav Agarwal Huichao Xie Anu Sathyan Sathyapalan Rema Michael J. Meaney Keith M. Godfrey Victor Samuel Rajadurai Lourdes Mary Daniel |
| author_facet | Pratibha Keshav Agarwal Huichao Xie Anu Sathyan Sathyapalan Rema Michael J. Meaney Keith M. Godfrey Victor Samuel Rajadurai Lourdes Mary Daniel |
| author_sort | Pratibha Keshav Agarwal |
| collection | DOAJ |
| description | Background: With increasing acceptance of universal developmental screening in primary care, it is essential to evaluate the local validity and psychometric properties of commonly used questionnaires like the parent-completed Ages and Stages Questionnaires, 3rd Edition (ASQ-3) in identifying developmental delays. The aim of this study is to assess the convergent validity of the ASQ-3 with the Bayley Scales of Infant Development-3rd edition (Bayley-III) in identifying developmental delay in a low-risk term cohort in Singapore. Methods: ASQ-3 and Bayley-III data was collected prospectively with generation of ASQ-3 cut-off scores using three different criteria: 1-standard deviation (SD) (Criterion-I) or 2-SD (Criterion-II) below the mean, and using a Receiver Operator Curve (ROC) (Criterion-III). Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values were calculated. Correlations between the ASQ-3 and Bayley-III domains were evaluated using Pearson coefficients. Results: With all three criteria across different domains ASQ-3 showed high specificity (72–99%) and NPV (69–98%), but lower sensitivity (19–74%) and PPV (11–59%). Criterion-I identified 11–21% of children as “at-risk of developmental delay,” and was the most promising criterion measure, with high specificity (82–91%), NPV (69–74%) and overall agreement of 64–71%. Moderate-strong correlations were seen between ASQ-3 Communication and Bayley-III Language scales (r = 0.44–0.59, p < 0.01). The lowest sensitivities were seen in the motor domains. Conclusions: ASQ-3 is reliable in low-risk settings in identifying typically developing children not at risk of developmental delay, but it has modest sensitivity. Moderate-strong correlations seen in the communication domain are clinically important for early identification of language delay, which is one of the most prevalent areas of early childhood developmental delay. |
| first_indexed | 2024-03-08T09:04:48Z |
| format | Article |
| id | doaj.art-c6f81b2e2529459ea36065a961179cb8 |
| institution | Directory Open Access Journal |
| issn | 1875-9572 |
| language | English |
| last_indexed | 2024-03-08T09:04:48Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj.art-c6f81b2e2529459ea36065a961179cb82024-02-01T06:29:49ZengElsevierPediatrics and Neonatology1875-95722024-01-016514854Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort studyPratibha Keshav Agarwal0Huichao Xie1Anu Sathyan Sathyapalan Rema2Michael J. Meaney3Keith M. Godfrey4Victor Samuel Rajadurai5Lourdes Mary Daniel6Dept of Child Development; KK Women's and Children's Hospital Singapore, Singapore; Corresponding author.Psychology and Child & Human Development, Nanyang Technological University National Institute of Education, SingaporeAgency for Science Technology and Research (A∗STAR), SingaporeMcGill University, CanadaMRC Life Course Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, UKDept of Neonatology, KK Women's and Children's Hospital Singapore, SingaporeDept of Child Development; KK Women's and Children's Hospital Singapore, SingaporeBackground: With increasing acceptance of universal developmental screening in primary care, it is essential to evaluate the local validity and psychometric properties of commonly used questionnaires like the parent-completed Ages and Stages Questionnaires, 3rd Edition (ASQ-3) in identifying developmental delays. The aim of this study is to assess the convergent validity of the ASQ-3 with the Bayley Scales of Infant Development-3rd edition (Bayley-III) in identifying developmental delay in a low-risk term cohort in Singapore. Methods: ASQ-3 and Bayley-III data was collected prospectively with generation of ASQ-3 cut-off scores using three different criteria: 1-standard deviation (SD) (Criterion-I) or 2-SD (Criterion-II) below the mean, and using a Receiver Operator Curve (ROC) (Criterion-III). Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values were calculated. Correlations between the ASQ-3 and Bayley-III domains were evaluated using Pearson coefficients. Results: With all three criteria across different domains ASQ-3 showed high specificity (72–99%) and NPV (69–98%), but lower sensitivity (19–74%) and PPV (11–59%). Criterion-I identified 11–21% of children as “at-risk of developmental delay,” and was the most promising criterion measure, with high specificity (82–91%), NPV (69–74%) and overall agreement of 64–71%. Moderate-strong correlations were seen between ASQ-3 Communication and Bayley-III Language scales (r = 0.44–0.59, p < 0.01). The lowest sensitivities were seen in the motor domains. Conclusions: ASQ-3 is reliable in low-risk settings in identifying typically developing children not at risk of developmental delay, but it has modest sensitivity. Moderate-strong correlations seen in the communication domain are clinically important for early identification of language delay, which is one of the most prevalent areas of early childhood developmental delay.http://www.sciencedirect.com/science/article/pii/S1875957223001237ASQ-3Bayley-IIIcohort studydevelopmental screeningvalidity |
| spellingShingle | Pratibha Keshav Agarwal Huichao Xie Anu Sathyan Sathyapalan Rema Michael J. Meaney Keith M. Godfrey Victor Samuel Rajadurai Lourdes Mary Daniel Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort study Pediatrics and Neonatology ASQ-3 Bayley-III cohort study developmental screening validity |
| title | Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort study |
| title_full | Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort study |
| title_fullStr | Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort study |
| title_full_unstemmed | Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort study |
| title_short | Concurrent validity of the ages and stages questionnaires with Bayley Scales of Infant Development-III at 2 years – Singapore cohort study |
| title_sort | concurrent validity of the ages and stages questionnaires with bayley scales of infant development iii at 2 years singapore cohort study |
| topic | ASQ-3 Bayley-III cohort study developmental screening validity |
| url | http://www.sciencedirect.com/science/article/pii/S1875957223001237 |
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