The role of imaging in the skeletal involvement of mucopolysaccharidoses
Abstract This article discusses the role of imaging modalities including radiography, multi-detector computed tomography, magnetic resonance imaging, and ultrasound in diagnosing and monitoring skeletal abnormalities in mucopolysaccharidoses (MPS). The advantages and disadvantages of these different...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-11-01
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| Series: | Italian Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13052-018-0556-z |
| _version_ | 1818096889256476672 |
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| author | Vincenzo Spina Domenico Barbuti Alberto Gaeta Stefano Palmucci Ernesto Soscia Marco Grimaldi Antonio Leone Renzo Manara Gabriele Polonara |
| author_facet | Vincenzo Spina Domenico Barbuti Alberto Gaeta Stefano Palmucci Ernesto Soscia Marco Grimaldi Antonio Leone Renzo Manara Gabriele Polonara |
| author_sort | Vincenzo Spina |
| collection | DOAJ |
| description | Abstract This article discusses the role of imaging modalities including radiography, multi-detector computed tomography, magnetic resonance imaging, and ultrasound in diagnosing and monitoring skeletal abnormalities in mucopolysaccharidoses (MPS). The advantages and disadvantages of these different imaging tools will be discussed, along with their feasibility in this class of patients. As the musculoskeletal involvement is common to all MPS and is one of the main reasons for seeking medical attention, an increased awareness among paediatricians, rheumatologists, orthopaedists, radiologists, and other musculoskeletal specialists on the possible spectrum of abnormalities observed could facilitate a timely diagnosis, an appropriate severity evaluation, and better management. |
| first_indexed | 2024-12-10T23:11:48Z |
| format | Article |
| id | doaj.art-c6f9cc7c496946b184c77a821becf4fc |
| institution | Directory Open Access Journal |
| issn | 1824-7288 |
| language | English |
| last_indexed | 2024-12-10T23:11:48Z |
| publishDate | 2018-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj.art-c6f9cc7c496946b184c77a821becf4fc2022-12-22T01:29:55ZengBMCItalian Journal of Pediatrics1824-72882018-11-0144S2677310.1186/s13052-018-0556-zThe role of imaging in the skeletal involvement of mucopolysaccharidosesVincenzo Spina0Domenico Barbuti1Alberto Gaeta2Stefano Palmucci3Ernesto Soscia4Marco Grimaldi5Antonio Leone6Renzo Manara7Gabriele Polonara8Division of General and Emergency Radiology, Sant’Agostino-Estense HospitalDepartment of Diagnostic Imaging, Pediatric Hospital Bambin GesùRadiology Unit, Pediatric Hospital Giovanni XXIIIRadiodiagnostic and Radiotherapy Unit, University Hospital Policlinico-Vittorio EmanueleBio-structures e Bio-imaging InstituteDepartment of Diagnostic Imaging, Neuroradiology, Humanitas Clinical and Research Center, IRCCS-RozzanoFondazione Policlinico Universitario Policlinico Gemelli IRCCS, Università Cattolica del Sacro CuoreNeuroradiology, Department of Medicine and Surgery, University of SalernoNeuroradiology Unit, University Hospital “Ospedali Riuniti di Ancona”, Politecnica University of MarcheAbstract This article discusses the role of imaging modalities including radiography, multi-detector computed tomography, magnetic resonance imaging, and ultrasound in diagnosing and monitoring skeletal abnormalities in mucopolysaccharidoses (MPS). The advantages and disadvantages of these different imaging tools will be discussed, along with their feasibility in this class of patients. As the musculoskeletal involvement is common to all MPS and is one of the main reasons for seeking medical attention, an increased awareness among paediatricians, rheumatologists, orthopaedists, radiologists, and other musculoskeletal specialists on the possible spectrum of abnormalities observed could facilitate a timely diagnosis, an appropriate severity evaluation, and better management.http://link.springer.com/article/10.1186/s13052-018-0556-zMucopolysaccharidosesMusculoskeletal involvementRadiographyUltrasoundMultidetector computed tomographyMagnetic resonance imaging |
| spellingShingle | Vincenzo Spina Domenico Barbuti Alberto Gaeta Stefano Palmucci Ernesto Soscia Marco Grimaldi Antonio Leone Renzo Manara Gabriele Polonara The role of imaging in the skeletal involvement of mucopolysaccharidoses Italian Journal of Pediatrics Mucopolysaccharidoses Musculoskeletal involvement Radiography Ultrasound Multidetector computed tomography Magnetic resonance imaging |
| title | The role of imaging in the skeletal involvement of mucopolysaccharidoses |
| title_full | The role of imaging in the skeletal involvement of mucopolysaccharidoses |
| title_fullStr | The role of imaging in the skeletal involvement of mucopolysaccharidoses |
| title_full_unstemmed | The role of imaging in the skeletal involvement of mucopolysaccharidoses |
| title_short | The role of imaging in the skeletal involvement of mucopolysaccharidoses |
| title_sort | role of imaging in the skeletal involvement of mucopolysaccharidoses |
| topic | Mucopolysaccharidoses Musculoskeletal involvement Radiography Ultrasound Multidetector computed tomography Magnetic resonance imaging |
| url | http://link.springer.com/article/10.1186/s13052-018-0556-z |
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