<i>SQSTM1/p62</i> Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma

<i>SQSTM1/p62</i> Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma

Migration and invasion play crucial roles in the progression of hepatocellular carcinoma (HCC), but the underlying mechanisms are not clear. Analysis of clinical samples indicates that SQSTM1/p62 is highly expressed in HCC and seriously affects the prognosis of patients. Subsequently, we showed that...

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Bibliographic Details
Main Authors: Jinghua Lu, Yipei Ding, Wanqiu Zhang, Yuanyuan Qi, Jin Zhou, Naihan Xu, Yaou Zhang, Weidong Xie
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
migration
invasion
hepatocellular carcinoma
SQSTM1/p62
Online Access:https://www.mdpi.com/2073-4409/12/9/1238

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