DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour biopsies

DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour biopsies

Abstract Background Tumour stem cells are considered important to promote disease progression, recurrence and treatment resistance following chemotherapy in colon cancer. However, genomic analyses of colorectal cancer have mainly been performed on integrated tumour tissue consisting of several diffe...

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Bibliographic Details
Main Authors: Diana Cervantes-Madrid, Yvonne Wettergren, Peter Falk, Kent Lundholm, Annika G. Asting
Format: Article
Language:English
Published: BMC 2017-03-01
Series:BMC Cancer
Subjects:
Cancer stem cells
CD133/Prominin1
colorectal cancer
copy number variations
DNA alterations
Online Access:http://link.springer.com/article/10.1186/s12885-017-3206-8

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