Intracoronary Sarcoplasmic Reticulum Calcium-ATPase Gene Therapy in Advanced Heart Failure Patients with reduced Ejection Fraction: A Prospective Cohort Study

Intracoronary Sarcoplasmic Reticulum Calcium-ATPase Gene Therapy in Advanced Heart Failure Patients with reduced Ejection Fraction: A Prospective Cohort Study

OBJECTIVE: Heart failure is a progressive and debilitating disease. Intracoronary sarcoplasmic reticulum calcium-ATPase gene therapy may improve the function of cardiac muscle cells. This study aimed to test the hypothesis that intracoronary sarcoplasmic reticulum calcium-ATPase gene therapy can imp...

Full description

Bibliographic Details
Main Authors:	Jianfeng Zhang, Guojin Hu, Shengyong Yang
Format:	Article
Language:	English
Published:	Elsevier España 2020-03-01
Series:	Clinics
Subjects:	Cardiac Events Ejection Fraction Heart Failure Intracoronary Delivery Sarcoplasmic Reticulum calcium-ATPase Gene Therapy
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100220&tlng=en

Similar Items

Targeting calcium regulators as therapy for heart failure: focus on the sarcoplasmic reticulum Ca-ATPase pump
by: Changwon Kho
Published: (2023-07-01)

Restoration of Sarcoplasmic Reticulum Ca<sup>2+</sup> ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice
by: Rizwan Qaisar, et al.
Published: (2020-12-01)

TRPC1 channels underlie stretch-modulated sarcoplasmic reticulum calcium leak in cardiomyocytes
by: Molly E. Streiff, et al.
Published: (2022-12-01)

Inhibition of the sarcoplasmic reticulum Ca2+ pump with thapsigargin to estimate the contribution of Na+-Ca2+ exchange to ventricular myocyte relaxation
by: Bassani R.A., et al.
Published: (2003-01-01)

Role of Reduced Sarco-Endoplasmic Reticulum Ca2+-ATPase Function on Sarcoplasmic Reticulum Ca2+ Alternans in the Intact Rabbit Heart
by: Lianguo Wang, et al.
Published: (2021-05-01)

Influence of Obesity and Type 2 Diabetes on Calcium Handling by Skeletal Muscle: Spotlight on the Sarcoplasmic Reticulum and Mitochondria
by: Hiroaki Eshima
Published: (2021-11-01)

Modulation of Cardiac Alternans by Altered Sarcoplasmic Reticulum Calcium Release: A Simulation Study
by: Jakub Tomek, et al.
Published: (2018-09-01)

Mitochondrial and Sarcoplasmic Reticulum Interconnection in Cardiac Arrhythmia
by: Felipe Salazar-Ramírez, et al.
Published: (2021-01-01)

Energy interconversion by the sarcoplasmic reticulum Ca2+-ATPase: ATP hydrolysis, Ca2+ transport, ATP synthesis and heat production
by: LEOPOLDO DE MEIS
Published: (2000-09-01)

Ca<sup>2+</sup> Dependent Formation/Collapse of Cylindrical Ca<sup>2+</sup>-ATPase Crystals in Scallop Sarcoplasmic Reticulum (SR) Vesicles: A Possible Dynamic Role of SR in Regulation of Muscle Contraction
by: Jun Nakamura, et al.
Published: (2023-04-01)

Cas9/AAV9-Mediated Somatic Mutagenesis Uncovered the Cell-Autonomous Role of Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 in Murine Cardiomyocyte Maturation
by: Junsen Lin, et al.
Published: (2022-04-01)

Atomistic Structure and Dynamics of the Ca<sup>2+</sup>-ATPase Bound to Phosphorylated Phospholamban
by: Rodrigo Aguayo-Ortiz, et al.
Published: (2020-10-01)

Elongation and Contraction of Scallop Sarcoplasmic Reticulum (SR): ATP Stabilizes Ca<sup>2+</sup>-ATPase Crystalline Array Elongation of SR Vesicles
by: Jun Nakamura, et al.
Published: (2022-03-01)

Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling
by: Allyson eKranstuber, et al.
Published: (2012-07-01)

Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice
by: Hiro Yamamoto, et al.
Published: (2022-09-01)

Observation of Network Dynamics of Ryanodine Receptors on Skeletal Muscle Sarcoplasmic Reticulum Membranes
by: Hongli Hu, et al.
Published: (2016-06-01)

Rats fed linseed oil in microemulsion forms enriches the cardiac sarcoplasmic reticulum lipids with docosahexaenoic acid and lower calcium transport
by: D. Sugasini, et al.
Published: (2013-10-01)

Effects of Sarcolemmal Background Ca2+ Entry and Sarcoplasmic Ca2+ Leak Currents on Electrophysiology and Ca2+ Transients in Human Ventricular Cardiomyocytes: A Computational Comparison
by: Molly E. Streiff, et al.
Published: (2022-06-01)

Unbalance Between Sarcoplasmic Reticulum Ca2 + Uptake and Release: A First Step Toward Ca2 + Triggered Arrhythmias and Cardiac Damage
by: Marilén Federico, et al.
Published: (2020-01-01)

Sarcoplasmic Reticulum-Mitochondria Kissing in Cardiomyocytes: Ca2+, ATP, and Undisclosed Secrets
by: Michela Rossini, et al.
Published: (2020-06-01)

Peptidyl‐Prolyl Isomerase 1 Regulates Ca2+ Handling by Modulating Sarco(Endo)Plasmic Reticulum Calcium ATPase and Na2+/Ca2+ Exchanger 1 Protein Levels and Function
by: Veronica Sacchi, et al.
Published: (2017-10-01)

Functional sympatholysis in mouse skeletal muscle involves sarcoplasmic reticulum swelling in arterial smooth muscle cells
by: Jennifer van derHorst, et al.
Published: (2021-12-01)

Changes in T-Tubules and Sarcoplasmic Reticulum in Ventricular Myocytes in Early Cardiac Hypertrophy in a Pressure Overload Rat Model
by: Perla Pérez-Treviño, et al.
Published: (2015-10-01)

PKC Inhibits Sec61 Translocon-Mediated Sarcoplasmic Reticulum Ca2+ Leak in Smooth Muscle Cells
by: Adan Dagnino-Acosta, et al.
Published: (2022-06-01)

Ultrastructure of primary pacemaking cells in rabbit sino‐atrial node cells indicates limited sarcoplasmic reticulum content
by: Ramesh Iyer, et al.
Published: (2020-02-01)

Effects of Bergamot Polyphenols on Mitochondrial Dysfunction and Sarcoplasmic Reticulum Stress in Diabetic Cardiomyopathy
by: Jessica Maiuolo, et al.
Published: (2021-07-01)

Calcium and Heart Failure: How Did We Get Here and Where Are We Going?
by: Natthaphat Siri-Angkul, et al.
Published: (2021-07-01)

Effects of Acute Exercise and Training on the Sarcoplasmic Reticulum Ca2+ Release and Uptake Rates in Highly Trained Endurance Athletes
by: Kasper Degn Gejl, et al.
Published: (2020-07-01)

ST elevation after intracoronary administration of Papaverine for fractional flow reserve estimation
by: R.K. Jain, et al.
Published: (2014-05-01)

The Effects of Aging on Sarcoplasmic Reticulum-Related Factors in the Skeletal Muscle of Mice
by: Yuji Kanazawa, et al.
Published: (2024-02-01)

Calcium dysregulation in heart diseases: Targeting calcium channels to achieve a correct calcium homeostasis
by: Giampaolo Morciano, et al.
Published: (2022-03-01)

β-Adrenergic Inhibition Prevents Action Potential and Calcium Handling Changes during Regional Myocardial Ischemia
by: Shannon R. Murphy, et al.
Published: (2017-08-01)

Ca<sup>2+</sup>-ATPase Molecules as a Calcium-Sensitive Membrane-Endoskeleton of Sarcoplasmic Reticulum
by: Jun Nakamura, et al.
Published: (2021-03-01)

Involvement of Ca2+-ATPase in suppressing the appearance of bovine helically motile spermatozoa with intense force prior to cryopreservation
by: DURITAHALA, et al.
Published: (2022-03-01)

Integrins Increase Sarcoplasmic Reticulum Activity for Excitation—Contraction Coupling in Human Stem Cell-Derived Cardiomyocytes
by: Brian X. Wang, et al.
Published: (2022-09-01)

REEP5 (Receptor Accessory Protein 5) Acts as a Sarcoplasmic Reticulum Membrane Sculptor to Modulate Cardiac Function
by: Lei Yao, et al.
Published: (2018-02-01)

Calcium Deregulation: Novel Insights to Understand Friedreich’s Ataxia Pathophysiology
by: Rosella Abeti, et al.
Published: (2018-10-01)

Disruption of Sarcoplasmic Reticulum‐Mitochondrial Contacts Underlies Contractile Dysfunction in Experimental and Human Atrial Fibrillation: A Key Role of Mitofusin 2
by: Jin Li, et al.
Published: (2022-10-01)

Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction
by: Craig L. Doig, et al.
Published: (2020-02-01)

Intracoronary tenecteplase for stent thrombosis
by: P.B. Jayagopal, et al.
Published: (2021-09-01)