Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer
Background So far, there is no reliable information on the drugs actually taken by tuberculosis patients. With billing data from a large German health insurance company, valid data from practice will be used for analysis. The objective here is to use the claims data of a health insurer to gain an in...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2020-07-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/6/3/00369-2019.full |
| _version_ | 1819072197805735936 |
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| author | Jan F. Kersten Stefanie Wobbe-Ribinski Roland Diel Albert Nienhaus Anja Schablon |
| author_facet | Jan F. Kersten Stefanie Wobbe-Ribinski Roland Diel Albert Nienhaus Anja Schablon |
| author_sort | Jan F. Kersten |
| collection | DOAJ |
| description | Background
So far, there is no reliable information on the drugs actually taken by tuberculosis patients. With billing data from a large German health insurance company, valid data from practice will be used for analysis. The objective here is to use the claims data of a health insurer to gain an insight into the prescriptions issued to patients with tuberculosis in Germany.
Methods
The study design encompasses a longitudinal, analytical observational study of selected insurance holders. Descriptive analyses of the outpatient drug supply of pulmonary tuberculosis patients are determined for 6 payroll years. We have studied whether different doses of tuberculosis medication are associated with age, sex, inpatient status and comorbidity. Quantile regression is used as a method to identify subgroups or characteristic dosages.
Results
The number of defined daily doses prescribed per patient varies among insurance holders and encompasses widely differing timeframes. Higher doses are observed with increasing age, as well as in patients with tuberculosis-related hospitalisations. The sex of the patient has no identifiable effect on the prescribed doses for any of the first-line tuberculosis drugs. Comorbidity partially has a significant impact on the duration and intensity of tuberculosis drug prescriptions. |
| first_indexed | 2024-12-21T17:33:54Z |
| format | Article |
| id | doaj.art-c6ff1fa40ace47559643ae1d15aea055 |
| institution | Directory Open Access Journal |
| issn | 2312-0541 |
| language | English |
| last_indexed | 2024-12-21T17:33:54Z |
| publishDate | 2020-07-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | ERJ Open Research |
| spelling | doaj.art-c6ff1fa40ace47559643ae1d15aea0552022-12-21T18:55:50ZengEuropean Respiratory SocietyERJ Open Research2312-05412020-07-016310.1183/23120541.00369-201900369-2019Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurerJan F. Kersten0Stefanie Wobbe-Ribinski1Roland Diel2Albert Nienhaus3Anja Schablon4 Competence Center for Epidemiology and Health Services Research for Healthcare Professionals (CVcare), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany DAK-Gesundheit, Hamburg, Germany Dept of Occupational Medicine, Public Health and Hazardous Substances, Institution for Statutory Accident Insurance and Prevention in the Health and Welfare Services (BGW), Hamburg, Germany Competence Center for Epidemiology and Health Services Research for Healthcare Professionals (CVcare), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany Competence Center for Epidemiology and Health Services Research for Healthcare Professionals (CVcare), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany Background So far, there is no reliable information on the drugs actually taken by tuberculosis patients. With billing data from a large German health insurance company, valid data from practice will be used for analysis. The objective here is to use the claims data of a health insurer to gain an insight into the prescriptions issued to patients with tuberculosis in Germany. Methods The study design encompasses a longitudinal, analytical observational study of selected insurance holders. Descriptive analyses of the outpatient drug supply of pulmonary tuberculosis patients are determined for 6 payroll years. We have studied whether different doses of tuberculosis medication are associated with age, sex, inpatient status and comorbidity. Quantile regression is used as a method to identify subgroups or characteristic dosages. Results The number of defined daily doses prescribed per patient varies among insurance holders and encompasses widely differing timeframes. Higher doses are observed with increasing age, as well as in patients with tuberculosis-related hospitalisations. The sex of the patient has no identifiable effect on the prescribed doses for any of the first-line tuberculosis drugs. Comorbidity partially has a significant impact on the duration and intensity of tuberculosis drug prescriptions.http://openres.ersjournals.com/content/6/3/00369-2019.full |
| spellingShingle | Jan F. Kersten Stefanie Wobbe-Ribinski Roland Diel Albert Nienhaus Anja Schablon Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer ERJ Open Research |
| title | Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer |
| title_full | Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer |
| title_fullStr | Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer |
| title_full_unstemmed | Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer |
| title_short | Influence of age, sex and hospitalisation on the administration of tuberculosis medication: an evaluation of routine data from a German health insurer |
| title_sort | influence of age sex and hospitalisation on the administration of tuberculosis medication an evaluation of routine data from a german health insurer |
| url | http://openres.ersjournals.com/content/6/3/00369-2019.full |
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